Mestranol

Mestranol

Systematic (IUPAC) name
3-Methoxy-19-nor-17α-pregna-1,3,5(10)-trien-20-yn-17-ol
Clinical data
AHFS/Drugs.com	International Drug Names
MedlinePlus	a601050
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	72-33-3 Y
ATC code	None
PubChem	CID 6291
DrugBank	DB01357
ChemSpider	6054 Y
UNII	B2V233XGE7 Y
KEGG	D00575 N
ChEBI	CHEBI:6784 N
ChEMBL	CHEMBL1201151 N
Synonyms	(8S,9S,13S,14S,17S)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol
Chemical data
Formula	C21H26O2
Mol. mass	310.43 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C21H26O2/c1-4-21(22)12-10-19-18-7-5-14-13-15(23-3)6-8-16(14)17(18)9-11-20(19,21)2/h1,6,8,13,17-19,22H,5,7,9-12H2,2-3H3/t17-,18-,19+,20+,21+/m1/s1 Y Key:IMSSROKUHAOUJS-MJCUULBUSA-N Y
N(what is this?)  (verify)

Mestranol is the 3-methyl ether of ethinylestradiol. It was the estrogen used in many of the first oral contraceptives.

It is a biologically inactive prodrug of ethinylestradiol to which it is demethylated in the liver with a conversion efficiency of 70% (50 µg of mestranol is pharmacokinetically bioequivalent to 35 µg of ethinylestradiol).^[1]

References

1. ^ Faigle, Johann W.; Schenkel, Lotte (1998). "Pharmacokinetics of estrogens and progestogens". In in Fraser, Ian S. (ed.). Estrogens and Progestogens in Clinical Practice. London: Churchill Livingstone. pp. 273–294. ISBN 0-443-04706-5. 

This drug article relating to the genito-urinary system is a stub. You can help Wikipedia by expanding it.v · Categories: Hormonal contraception Synthetic estrogens Prodrugs Genito-urinary system drug stubs Wikimedia Foundation. 2010. Игры ⚽ Поможем написать реферат Trichoptilosis Pataria Look at other dictionaries: mestranol — el 3 metil éter del etinil estradiol, utilizado como estrógeno en varios anticonceptivos orales estructura química Diccionario ilustrado de Términos Médicos.. Alvaro Galiano. 2010 …   Diccionario médico Mestranol — Strukturformel Allgemeines Freiname Mestranol Andere Namen …   Deutsch Wikipedia mestranol — noun Etymology: meth + estrogen + pregnane (C21H36) + 1 ol Date: 1962 a synthetic estrogen C21H26O2 used in oral contraceptives …   New Collegiate Dictionary mestranol — /mes treuh nawl , nol /, n. Pharm. an estrogen, C21H26O2, used in oral contraceptives in combination with a progestin. [1960 65; contr. and rearrangement of methoxy and ethynylestradiol, components of the chemical name] * * * …   Universalium mestranol — The 3 methyl ether of ethynyl estradiol; an estrogen used in many oral contraceptive preparations. * * * mes·tra·nol mes trə .nȯl, .nōl n a synthetic estrogen C21H26O2 used in birth control pills see …   Medical dictionary mestranol — mes·tra·nol …   English syllables mestranol — n. a synthetic female sex hormone (see oestrogen) used in combination with a progestogen (norethisterone) as an oral contraceptive. Trade names: Norinyl 1 …   The new mediacal dictionary mestranol — noun a synthetic form of estrogen used in combination with a progestin in oral contraceptives • Hypernyms: ↑estrogen, ↑oestrogen • Substance Holonyms: ↑Enovid, ↑Norinyl, ↑Ovulen …   Useful english dictionary diacetato de etinodiol y mestranol — Contraceptivo oral. Diccionario Mosby Medicina, Enfermería y Ciencias de la Salud, Ediciones Hancourt, S.A. 1999 …   Diccionario médico Местранол (Mestranol) — синтетический женский половой гормон (см. Эстроген); применяется в сочетании с прогестороном для лечения симптомов менопаузы (см. Терапия гормонозаместительная), а также в качестве одной из составляющих в оральных контрацептивах. Торговые… …   Медицинские термины 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”