- Norethisterone acetate
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Norethisterone acetate Systematic (IUPAC) name (17α)-17-ethynyl-3-oxoestr-4-en-17-yl acetate Clinical data AHFS/Drugs.com International Drug Names MedlinePlus a604034 Pregnancy cat. ? Legal status ? Routes Oral Identifiers CAS number 38673-38-0 ATC code ? PubChem CID 63021 ChEMBL CHEMBL1201146 Chemical data Formula C22H28O3 Mol. mass 340.456 g/mol (what is this?) acetate (verify) Norethisterone acetate (INNM) or norethindrone acetate is a progestin used in contraception. It is the acetate ester of norethisterone.
Norethisterone (or norethindrone) (or 19-nor-17α-ethynyltestosterone) is a molecule used in some combined oral contraceptive pills and in some progestogen only pills. It is a progestogen and can be used to treat premenstrual syndrome, painful periods, abnormal heavy bleeding, irregular periods, menopausal syndrome (in combination with oestrogen), or to postpone a period. Norethindrone was the first orally highly active progestin to be synthesized. It was synthesized for the first time by chemists Luis Miramontes, Carl Djerassi, and George Rosenkranz at Syntex in Mexico City in 1951. It was the progestin used in one of the first two oral contraceptives. It is often used as the related ester, norethisterone acetate.
Estrogens and progestogens (G03C-D, L02) Progestogens/
progestins
(progesterone)AgonistAndrostene (Drospirenone) • 19-norprogesterone (Nomegestrol • Promegestone • Trimegestone) • 19-nortestosterone (Dienogest)Other/
ungroupedPregnenedione (Gestonorone) • Pregnene (Ethisterone) • Pregnadiene (Medrogestone • Melengestrol) • Norpregnane (Norgestrienone) • Lynestrenol • Norethynodrel • Tibolone • Dydrogesterone • Quingestanolantagonist: MifepristoneAsoprisnil • CDB-4124 • Ulipristal acetateEstrogens AgonistDiosgenin • Estradiol (Ethinylestradiol#/Mestranol • Estradiol 17 beta-cypionate# • Polyestradiol phosphate) • Estrone (Estrone sulfate) • Estriol • Promestriene • Equilenin • EquilinAfimoxifene • Arzoxifene • Bazedoxifene • Cyclofenil • Lasofoxifene • Ormeloxifene • Raloxifene • Tamoxifen • Toremifenepure antagonist: Fulvestrant#WHO-EM. ‡Withdrawn from market. Clinical trials: †Phase III. §Never to phase III This pharmacology-related article is a stub. You can help Wikipedia by expanding it.