Chlormadinone

Chlormadinone
Chlormadinone
Systematic (IUPAC) name
(9S,14S,17R)-17-acetyl-6-chloro-17-hydroxy-10,13-dimethyl-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one
Clinical data
AHFS/Drugs.com International Drug Names
Pregnancy cat.  ?
Legal status ℞ Prescription only
Routes Oral
Identifiers
CAS number 1961-77-9
ATC code G03DB06
PubChem CID 16065
ChemSpider 4447590
UNII SDS4N642GG YesY
KEGG D07670
Chemical data
Formula C21H27ClO3 
Mol. mass 362.89 g/mol
SMILES eMolecules & PubChem

Chlormadinone (INN) is a progestagen.

Synthesis

Chlormadinone synthesis.png

Bruckner, K.; Hampel, B.; Johnson, V.; Chem. Ber. 1961, 94, 1225.

http://dx.doi.org/10.1002/cber.19610940510

v · d · eEstrogens and progestogens (G03C-D, L02)
Progestogens/
progestins
(progesterone)
Agonist
Androstene (Drospirenone) • 19-norprogesterone (Nomegestrol • Promegestone • Trimegestone) • 19-nortestosterone (Dienogest)
Other/
ungrouped
Pregnenedione (Gestonorone) • Pregnene (Ethisterone) • Pregnadiene (Medrogestone • Melengestrol) • Norpregnane (Norgestrienone) • Lynestrenol • Norethynodrel • Tibolone • Dydrogesterone • Quingestanol
antagonist: Mifepristone
Asoprisnil • CDB-4124  • Ulipristal acetate
Estrogens
Agonist
Diosgenin • Estradiol (Ethinylestradiol#/Mestranol • Estradiol 17 beta-cypionate# • Polyestradiol phosphate) • Estrone (Estrone sulfate) • Estriol • Promestriene • Equilenin • Equilin
#WHO-EM. ‡Withdrawn from market. Clinical trials: †Phase III. §Never to phase III

M: ♀ FRS

anat/phys/devp

noco/cong/npls, sysi/epon

proc/asst, drug (G1/G2B/G3CD)
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