Vorozole

Drugbox
IUPAC_name = 6- [(4-chlorophenyl)-(1,2,4-triazol-1-yl)methyl] -
1-methyl-benzotriazole

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CAS_number=118949-22-7
ATC_prefix=L02
ATC_suffix=BG05
ATC_supplemental=
PubChem=60796
DrugBank=
C = 16 | H = 13 | Cl = 1 | N = 6
molecular_weight = 324.768 g/mol
bioavailability= Very high
metabolism = Hepatic
elimination_half-life= 8 hours
excretion =
pregnancy_category =
legal_status =
routes_of_administration=

Vorozole is an imidazole based competitive inhibitor of the aromatase enzyme. It underwent clinical testing for evaluation for use as an antineoplastic agent; however it was withdrawn from testing when no difference was detected in the duration of median survival as compared to the progestational agent megestrol acetate and research instead focused on the other third generation aromatase inhibitors anastrozole, letrozole and exemestane.