CDB-4124

Drugbox
IUPAC_name = 17α-acetoxy-21-methoxy-11β- [4-N,N-dimethylaminophenyl] -19-norpregna-4,9-diene-3,20-dione)

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CAS_number = 136960-00-4
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PubChem = 9577221
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chemical_formula =
C=31 | H=39 | N=1 | O=5
molecular_weight = 505.65 g/mol
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legal_status = Investigational
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CDB-4124 (proposed trade names Proellex, Progenta) is an investigational selective progesterone receptor modulator, tested for treatment of progesterone sensitive myomata. [cite journal |author=Attardi BJ, Burgenson J, Hild SA, Reel JR |title=In vitro antiprogestational/antiglucocorticoid activity and progestin and glucocorticoid receptor binding of the putative metabolites and synthetic derivatives of CDB-2914, CDB-4124, and mifepristone |journal=J Steroid Biochem Mol Biol |volume=88 |issue=3 |pages=277–88 |year=2004 |pmid= 15120421 |doi = 10.1016/j.jsbmb.2003.12.004 ]

as of|September 2008, it is undergoing Phase II and III clinical trials. [ [http://www.clinicaltrials.gov/ct2/results?term=Proellex ClinicalTrials.gov] ]

References