Marchiafava-Bignami disease
- Marchiafava-Bignami disease
-
Marchiafava-Bignami disease is a progressive neurological disease characterized by corpus callosum demyelination and necrosis and subsequent atrophy.
Eponym
It was first described in 1903 by the Italian pathologists Amico Bignami and Ettore Marchiafava in an Italian Chianti drinker.[1][2] In this patient, Marchiafava and Bignami noticed that the middle two-thirds of the corpus callosum were necrotic.
Causes
It is classically associated with chronic alcoholics and sometimes nutritional deficiencies.
See also
Central pontine myelinolysis
References
- ^ synd/2922 at Who Named It?
- ^ E. Marchiafava, A. Bignami. Sopra un' alterazione del corpo calloso osservata da sogetti alcoolisti. Rivista di patologia nervosa e mentale, 1903, 8 (12): 544-549.
External links
v · d · ePathology of the nervous system, primarily CNS (G04–G47, 323–349) |
|
Inflammation |
|
|
Brain/
encephalopathy |
|
|
|
|
autoimmune ( Multiple sclerosis, Neuromyelitis optica, Schilder's disease) · hereditary ( Adrenoleukodystrophy, Alexander, Canavan, Krabbe, ML, PMD, VWM, MFC, CAMFAK syndrome) · Central pontine myelinolysis · Marchiafava-Bignami disease · Alpers' disease
|
|
Episodic/
paroxysmal
|
|
|
|
|
|
Other
|
|
|
|
Spinal cord/
myelopathy |
|
|
Both/either |
|
|
|
|
noco(m/d/e/h/v/s)/cong/tumr, sysi/epon, injr
|
proc, drug(N1A/2AB/C/3/4/7A/B/C/D)
|
|
|
|
|
Categories: - Disease stubs
- Demyelinating diseases of CNS
Wikimedia Foundation.
2010.
Look at other dictionaries:
Marchiafava-Bignami disease — Mar·chi·a·fa·va Bi·gna·mi disease (mahr″ke ə fahґvah be nyahґme) [Ettore Marchiafava, Italian pathologist, 1847–1935; Amico Bignami, Italian pathologist, 1862–1929] see under disease … Medical dictionary
Marchiafava-Bignami disease — progressive degeneration of the corpus callosum characterized by progressive intellectual deterioration, emotional disturbances, confusion, hallucinations, tremor, rigidity, and convulsions. It is a very rare disorder affecting chiefly middle… … Medical dictionary
Disease — Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the… … Medical dictionary
Bignami — Amico, Italian physician, 1862–1929. See Marchiafava B. disease … Medical dictionary
Marchiafava — Ettore, Italian pathologist, 1847–1935. See M. Bignami disease, M. Micheli anemia, M. Micheli syndrome … Medical dictionary
Ettore Marchiafava — Ettore Marchiafava( 1847, Rome 1935, Rome) was an Italian physician and zoologist who worked on malariaEttore Marchiafava , was the personal doctor of three popes and the Royal House of Savoy, a senator and professor of Pathological Anatomy at… … Wikipedia
Amico Bignami — (15 April 1862 , Bologna 8 September 1919 , Rome was an Italian physician and entomologist Bignami graduated as a doctor in Rome in 1882. In 1883, he became extraordinary professor of pathology and in 1906, full time professor at the University… … Wikipedia
Huntington's disease — Classification and external resources A microscope image of … Wikipedia
Wilson's disease — Classification and external resources A Kayser Fleischer ring (the brown ring on the edge of the iris) is common in Wilson s disease, especially when neurological symptoms are present ICD … Wikipedia
Parkinson's disease — Parkinson s redirects here. For other uses, see Parkinson s (disambiguation). Parkinson s disease Classification and external resources … Wikipedia