Bucladesine

Bucladesine

Systematic (IUPAC) name
sodium (3aR,4R,6R,6aR)-4-(6-butanamido-9H-purin-9-yl)-6-[(butanoyloxy)methyl]-2-oxo-tetrahydro-2H-1,3,5,2λ5-furo[3,4-d][1,3,2]dioxaphosphol-2-olate
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	362-74-3
ATC code	C01CE04
PubChem	CID 28177
ChemSpider	9306 Y
UNII	63X7MBT2LQ Y
ChEBI	CHEBI:50095 Y
ChEMBL	CHEMBL485980 Y
Synonyms	• Dibutyryl cyclic adenosine monophosphate • (N6,2'-O-dibutyryl)-adenosine-3',5'-mono-phosphate • Dibutyryl cAMP • DcAMP • DBcAMP
Chemical data
Formula	C18H23N5NaO8P
Mol. mass	491.368 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C18H24N5O8P/c1-3-5-11(24)22-16-13-17(20-8-19-16)23(9-21-13)18-15(30-12(25)6-4-2)14-10(29-18)7-28-32(26,27)31-14/h8-10,14-15,18H,3-7H2,1-2H3,(H,26,27)(H,19,20,22,24)/t10-,14-,15-,18-/m1/s1 Y Key:CJGYSWNGNKCJSB-YVLZZHOMSA-N Y
Y(what is this?)  (verify)

Bucladesine is a cyclic nucleotide derivative which mimics the action of endogenous cAMP and is a phosphodiesterase inhibitor.

Bucladesine is a cell permeable cAMP analog. The compound is used in a wide variety of research applications because it mimics cAMP and can induce normal physiological responses when added to cells in experimental conditions. cAMP is only able to elicit minimal responses in these situations.

External links

• MeSH Bucladesine

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