EHNA

EHNA

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IUPAC_name = 3-(6-aminopurin-9-yl)nonan-2-ol hydrochloride


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CAS_number = 59262-86-1
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PubChem = 359137
DrugBank =
C = 14 | H = 24 | Cl = 1 | N = 5 | O = 1
molecular_weight = 313.826 g/mol
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EHNA (erythro-9-(2-hydroxy-3-nonyl)adenine) is a phosphodiesterase inhibitor that selectively inhibits phosphodiesterase type-2 (PDE2). [Podzuweit T, Nennstiel P and Muller A (1995) "Isozyme selective inhibition of cGMP-stimulated cyclic nucleotide phosphodiesterases by erythro-9-(2-hydroxy-3-nonyl) adenine". "Cell Signal" 7:733-8. PMID 8519602] [Méry PF, Pavoine C, Pecker F and Fischmeister R (1995). "Erythro-9-(2-hydroxy-3-nonyl)adenine inhibits cyclic GMP-stimulated phosphodiesterase in isolated cardiac myocytes". "Mol Pharmacol" 48:121-130 PMID 7623766]

References


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