Dopexamine

Dopexamine

Systematic (IUPAC) name
4-[2-({6-[(2-phenylethyl)amino]hexyl}amino)ethyl]benzene-1,2-diol
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	86197-47-9
ATC code	C01CA14
PubChem	CID 55483
ChemSpider	50102 Y
UNII	398E7Z7JB5 Y
KEGG	D03891 Y
ChEMBL	CHEMBL77622 Y
Chemical data
Formula	C22H32N2O2
Mol. mass	429.43 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C22H32N2O2/c25-21-11-10-20(18-22(21)26)13-17-24-15-7-2-1-6-14-23-16-12-19-8-4-3-5-9-19/h3-5,8-11,18,23-26H,1-2,6-7,12-17H2 Y Key:RYBJORHCUPVNMB-UHFFFAOYSA-N Y
Y(what is this?)  (verify)

Dopexamine is a β₂-adrenergic receptor agonist. It also acts at dopamine receptors.^[1]

Use in sepsis has been proposed.^[2]

It is considered a inotropic agent.^[3]

References

1. ^ Brown RA, Dixon J, Farmer JB, et al. (July 1985). "Dopexamine: a novel agonist at peripheral dopamine receptors and beta 2-adrenoceptors". Br. J. Pharmacol. 85 (3): 599–608. PMC 1916510. PMID 2862944. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1916510. 
2. ^ Birnbaum J, Klotz E, Spies CD, et al. (2006). "Effects of dopexamine on the intestinal microvascular blood flow and leucocyte activation in a sepsis model in rats". Crit Care 10 (4): R117. doi:10.1186/cc5011. PMC 1750974. PMID 16893450. http://ccforum.com/content/10/4/R117. 
3. ^ Lisbon A (May 2003). "Dopexamine, dobutamine, and dopamine increase splanchnic blood flow: what is the evidence?". Chest 123 (5 Suppl): 460S–3S. doi:10.1378/chest.123.5_suppl.460S. PMID 12740229. http://www.chestjournal.org/cgi/pmidlookup?view=long&pmid=12740229. 

This drug article relating to the cardiovascular system is a stub. You can help Wikipedia by expanding it.v · Categories: Beta-adrenergic agonists Catecholamines Dopamine agonists Inotropic agents Cardiovascular system drug stubs Wikimedia Foundation. 2010. Игры ⚽ Нужно решить контрольную? Charles W. Engelhard, Jr. Daily Money Management Services Look at other dictionaries: Methoxamine — Not to be confused with methoxetamine. Methoxamine Systematic (IUPAC) name 2 amino 1 (2,5 dimethoxyphenyl)propan 1 ol Clinical data …   Wikipedia Methylbenzodioxolylpentanamine — IUPAC name 1 (1,3 benzodioxol 5 yl) N methylpentan 2 amine …   Wikipedia Ethylbenzodioxolylpentanamine — IUPAC name 1 (1,3 benzodioxol 5 yl) N ethylpentan 2 amine …   Wikipedia Methylenedioxyhydroxyamphetamine — Systematic (IUPAC) name %28%C2%B1%29 1 %28benzo[d][1%2C3]dioxol 5 yl%29 N hydroxylpropan 2 amine Clinical data Trade names …   Wikipedia Methylenedioxyhydroxymethamphetamine — Systematic (IUPAC) name (±) 1 (benzo[d][1,3]dioxol 5 yl) N hydroxyl N methylpropan 2 amine Clinical data Pregnancy cat …   Wikipedia Ethylbenzodioxolylbutanamine — IUPAC name (1 Benzo[1,3]dioxol 5 ylmethyl propyl) ethyl amine …   Wikipedia Amphetamine — For other uses, see Amphetamine (disambiguation). Amphetamine Systematic (IUPAC) name …   Wikipedia Epinephrine — Adrenaline and Adrenalin redirect here. For other uses, see Adrenaline (disambiguation). (R) (–) L Epinephrine or (R) (–) L adrenaline …   Wikipedia Pseudoephedrine — Systematic (IUPAC) name ( …   Wikipedia Methylphenidate — Concerta redirects here. For the musical composition, see Concerto. For the implantable defibrillator named Medtronic Concerto, see defibrillator. Methylphenidate …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”