Sappinia amoebic encephalitis

Sappinia amoebic encephalitis

Sappinia amoebic encephalitis (SAE) is the name for amoebic encephalitis caused by species of Sappinia.[1]

The causative organism was originally identified as Sappinia diploidea,[2][3] but is now considered to be Sappinia pedata.[4]

It has been treated with azithromycin, pentamidine, itraconazole, and flucytosine.[3]

References

  1. ^ Da Rocha-Azevedo, B.; Tanowitz, H.; Marciano-Cabral, F. (2009). "Diagnosis of infections caused by pathogenic free-living amoebae". Interdisciplinary perspectives on infectious diseases 2009: 251406. doi:10.1155/2009/251406. PMC 2719787. PMID 19657454. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2719787.  edit
  2. ^ Gelman, B. B.; Rauf, S. J.; Nader, R.; Popov, V.; Borkowski, J.; Chaljub, G.; Nauta, H. W.; Visvesvara, G. S. (2001). "Amoebic encephalitis due to Sappinia diploidea". JAMA : the journal of the American Medical Association 285 (19): 2450–2451. doi:10.1001/jama.285.19.2450. PMID 11368696.  edit
  3. ^ a b Gelman, B. B.; Popov, V.; Chaljub, G.; Nader, R.; Rauf, S. J.; Nauta, H. W.; Visvesvara, G. S. (2003). "Neuropathological and ultrastructural features of amebic encephalitis caused by Sappinia diploidea". Journal of neuropathology and experimental neurology 62 (10): 990–998. PMID 14575235.  edit
  4. ^ Qvarnstrom, Y.; Da Silva, A.; Schuster, F.; Gelman, B.; Visvesvara, G. (2009). "Molecular confirmation of Sappinia pedata as a causative agent of amoebic encephalitis". The Journal of infectious diseases 199 (8): 1139–1142. doi:10.1086/597473. PMID 19302010.  edit
v · d · eInfectious diseases – Parasitic disease: protozoan infection: Amoebozoa diseases (A06, 006)
Lobosea
(free-living)
Centramoebida
Sappinia diploidea/Sappinia pedata (Sappinia amoebic encephalitis)
Conosa/Archamoebae
Entamoeba histolytica (Entamoebiasis, Amoebic dysentery, Amoebic liver abscess, Cutaneous entamoebiasis, Amoebic brain abscess, Amebiasis cutis) · Entamoeba gingivalis

M: PRO

ambz, excv, chrm (strc)

ambz, excv, chrm

ambz, excv, chrm
v · d · ePathology of the nervous system, primarily CNS (G04–G47, 323–349)
Inflammation
Encephalitis (Viral encephalitis, Herpesviral encephalitis) · Cavernous sinus thrombosis · Brain abscess (Amoebic)
Both/either
Brain/
encephalopathy
Episodic/
paroxysmal
Intracranial hypertension (Hydrocephalus/NPH, Idiopathic intracranial hypertension) · Cerebral edema · Intracranial hypotension
Other
Brain herniation · Reye's · Hepatic encephalopathy · Toxic encephalopathy
Spinal cord/
myelopathy
Both/either
UMN only: PLS · PP · HSP
both: ALS

M: CNS

anat(n/s/m/p/4/e/b/d/c/a/f/l/g)/phys/devp

noco(m/d/e/h/v/s)/cong/tumr, sysi/epon, injr

proc, drug(N1A/2AB/C/3/4/7A/B/C/D)

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