Nepafenac

Nepafenac: Nepafenac

Systematic (IUPAC) name

2-amino-3-benzoylbenzeneacetamide

Clinical data

AHFS/Drugs.com monograph

MedlinePlus a606007

Pregnancy cat. C

Legal status ℞-only (US)

Routes Ophthalmic

Identifiers

ATC code S01BC10

PubChem CID 151075

DrugBank DB06802

ChemSpider 133160^Y

UNII 0J9L7J6V8C^Y

KEGG D05143^Y

ChEMBL CHEMBL1021^Y

Chemical data

Formula C₁₅H₁₄N₂O₂

Mol. mass 254.28 g/mol

SMILES eMolecules & PubChem

InChI

InChI=1S/C15H14N2O2/c16-13(18)9-11-7-4-8-12(14(11)17)15(19)10-5-2-1-3-6-10/h1-8H,9,17H2,(H2,16,18)^Y
Key:QEFAQIPZVLVERP-UHFFFAOYSA-N^Y

Y(what is this?) (verify)

Nepafenac is a non-steroidal anti-inflammatory drug (NSAID), usually sold as a prescription eye drop (0.1% solution. Nepafenac is manufactured by Alcon as Nevanac. It is used to treat pain and inflammation associated with cataract surgery.

The usual dose is 1 drop in each affected eye beginning 1 day prior to cataract surgery, continued on the day of surgery and through the first 2 weeks of the postoperative period.

Its side effects may include decreased visual acuity, a feeling that something is in the eye, increased eye pressure or a sticky sensation, as well as other effects.

External links

Nevanac website

v · d · eNon-steroidal anti-inflammatory drug (NSAID) products (primarily M01A and M02A, also N02BA)

Salicylates
Aspirin (acetylsalicylic acid) • Aloxiprin • Benorylate • Diflunisal • Ethenzamide • Magnesium salicylate • Methyl salicylate • Salsalate • Salicin • Salicylamide • Sodium salicylate

Arylalkanoic acids
Diclofenac • Aceclofenac • Acemetacin • Alclofenac • Bromfenac • Etodolac • Indometacin • Indometacin farnesil • Nabumetone • Oxametacin • Proglumetacin • Sulindac • Tolmetin

2-Arylpropionic acids
(profens)
Ibuprofen • Alminoprofen • Benoxaprofen • Carprofen • Dexibuprofen • Dexketoprofen • Fenbufen • Fenoprofen • Flunoxaprofen • Flurbiprofen • Ibuproxam • Indoprofen^† • Ketoprofen • Ketorolac • Loxoprofen • Miroprofen • Naproxen • Oxaprozin • Pirprofen • Suprofen • Tarenflurbil • Tiaprofenic acid

N-Arylanthranilic acids
(fenamic acids)
Mefenamic acid • Flufenamic acid • Meclofenamic acid • Tolfenamic acid

Pyrazolidine derivatives
Phenylbutazone • Ampyrone • Azapropazone • Clofezone • Kebuzone • Metamizole • Mofebutazone • Oxyphenbutazone • Phenazone • Sulfinpyrazone

Oxicams
Piroxicam • Droxicam • Lornoxicam • Meloxicam • Tenoxicam • Ampiroxicam

COX -2 inhibitors
Celecoxib • Deracoxib^‡ • Etoricoxib • Firocoxib^‡ • Lumiracoxib^† • Parecoxib • Rofecoxib^† • Valdecoxib^†

Sulfonanilides
Nimesulide

Topically used products
Bendazac • Diclofenac • Etofenamate • Felbinac • Flurbiprofen • Ibuprofen • Indometacin • Ketoprofen • Naproxen • Piroxicam • Suprofen

COX-inhibiting nitric oxide donators
Naproxcinod

Others
Fluproquazone

Items listed in bold indicate initially developed compounds of specific groups. ^†Withdrawn drugs. ^‡Veterinary use medications.

Categories:
Non-steroidal anti-inflammatory drugs

Nepafenac

Systematic (IUPAC) name
2-amino-3-benzoylbenzeneacetamide
Clinical data
AHFS/Drugs.com	monograph
MedlinePlus	a606007
Pregnancy cat.	C
Legal status	℞-only (US)
Routes	Ophthalmic
Identifiers
ATC code	S01BC10
PubChem	CID 151075
DrugBank	DB06802
ChemSpider	133160^Y
UNII	0J9L7J6V8C^Y
KEGG	D05143^Y
ChEMBL	CHEMBL1021^Y
Chemical data
Formula	C₁₅H₁₄N₂O₂
Mol. mass	254.28 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C15H14N2O2/c16-13(18)9-11-7-4-8-12(14(11)17)15(19)10-5-2-1-3-6-10/h1-8H,9,17H2,(H2,16,18)^Y Key:QEFAQIPZVLVERP-UHFFFAOYSA-N^Y
Y(what is this?) (verify)

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nepafenac — noun A nonsteroidal anti inflammatory drug used to treat pain and inflammation associated with cataract surgery … Wiktionary

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