Islet cell carcinoma

Islet cell carcinoma
Islet cell carcinoma
Classification and external resources

A symptomatic patient with pheochromocytoma and islet cell tumor of the pancreas. A small right pheochromocytoma with a necrotic center (P) is seen. In addition, an intensely enhancing mass is present in the neck of the pancreas (I). Two small pancreatic cysts are also seen but the bulk of the pancreas is spared.
ICD-O: M8150/3
MeSH D018273

Islet cell carcinoma or nesidioblastoma is an uncommon cancer of the endocrine pancreas.

It accounts for approximately 1.3% of pancreatic cancer.[1]

The term "nesidioblastoma" dates to at least 1938.[2]


Survival in islet cell carcinoma is highly dependent upon the degree of disease involvement; surgical cure is possible if the tumor is resected completely. Review articles using the Surveillance Epidemiology and End Results (SEER) national database have shown a median survival of about a decade for localized disease, six years for regional (confined to the region of the pancreas) and two years for those with distant disease.[3]

See also