Hurthle cell

Hurthle cell

Infobox_Disease
Name = PAGENAME


Caption =
DiseasesDB = 31956
ICD10 = C73.9
ICD9 =
ICDO = 8290/0
OMIM =
MedlinePlus =
eMedicineSubj = med
eMedicineTopic = 1045
MeshID = D018249A Hürthle cell (also known, incorrectly as Askanazy cell. Askanazy cells are interfollicular C-cells) is an oncocytic cell in the thyroid that is often associated with Hashimoto's thyroiditis as well as follicular thyroid cancer.

Histology

Hürthle cells are characterized as enlarged epithelial cells with abundant eosinophilic granular cytoplasm as a result of altered mitochondria.cite web|url=http://www.emedicine.com/med/topic1045.htm |title=Hurthle Cell Carcinoma |author=Aytug, Serhat |publisher=eMedicine |date=June 13, 2006] They generally stain pink and are prominently found in histological sections of thyroid glands affected with Hashimoto's.

Clinical significance

A "Hürthle cell adenoma" is a well-differentiated type of follicular thyroid adenoma (benign tumor) that, in rare cases, has the potential to become malignant and metastasize ("Hürthle cell carcinoma").

Eponym

It is named for Karl Hürthle. [WhoNamedIt|synd|2742] [M. Askanazy. Pathologisch-anatomische Beiträge zur Kenntniss des morbus basedowii, insbesondere uber die dabei auftretende Muskelerkrankkung. Deutsches Archiv für klinische Medicin, Leipzig, 1898, 61:118-186. ]

ee also

* adenoma
* oncocytoma
* oxyphil cell

References

External links

* [http://www.thedoctorsdoctor.com/diseases/hurthle_cell_tumors.htm The Doctor's Doctor]
* [http://www.thyroidmanager.org/Chapter18/18-pathology.htm Illustration]
* [http://www.endocrineweb.com/hurthle.html EndocrineWeb]
* [http://www.hku.hk/patho/pracs/endo/prac2/34a.htm HKU]
* [http://path.upmc.edu/cases/case45/images/micro4.jpgImage]

References


Wikimedia Foundation. 2010.

Игры ⚽ Поможем решить контрольную работу

Look at other dictionaries:

  • Hürthle cell tumour — a malignant tumour of the thyroid gland that arises from Hürthle (or Askanazy) cells, altered follicular cells of the gland that have large nuclei and stain deeply with eosin (these cells are also found in benign nodules and Hashimoto s disease) …   The new mediacal dictionary

  • Hürthle cell tumour — a malignant tumour of the thyroid gland that arises from Hürthle cells, large eosinophilic cells occasionally occurring in the gland. This carcinoma is not as common as papillary, follicular, or anaplastic thyroid carcinomas. K. W. Hürthle (1860… …   Medical dictionary

  • Hurthle cell neoplasm — An uncommon type of thyroid tumor that can be benign or malignant …   English dictionary of cancer terms

  • Cell — The basic structural and functional unit in people and all living things. Each cell is a small container of chemicals and water wrapped in a membrane. Each cell in the human body there are 100 trillion cells in each of us contains the entire… …   Medical dictionary

  • List of topics in cell biology — Cell invokes a major branch of theory and research known variously as cell biology, cellular biology or cytology. The study of cell tissues is known as histology. Cell types are often referred to using the suffixes blast, clast, cyte, especially… …   Wikipedia

  • Hürthle — Karl W., German histologist, 1860–1945. See H. cell, H. cell adenoma, H. cell carcinoma …   Medical dictionary

  • Karl Hürthle — (March 16, 1860 1945) was a German physiologist and histologist who was a native of Ludwigsburg.In 1884 he received his doctorate from the University of Tübingen, where he remained until 1886, working as a prosector at the anatomical institute.… …   Wikipedia

  • Renal cell carcinoma — For other uses, see RCC (disambiguation). Main article: Kidney cancer Renal cell carcinoma Classification and external resources Micrograph of the most common t …   Wikipedia

  • Basal-cell carcinoma — Classification and external resources A basal cell carcinoma ICD 10 C44 (ILDS C44.L21) ICD 9 …   Wikipedia

  • Squamous-cell carcinoma — Squamous cell carcinoma, NOS Classification and external resources SCC of the skin tends to arise from pre malignant lesions, actinic keratoses; surface is usually scaly and often ulcerates (as shown here). ICD 10 …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”