DNAJC10

DnaJ (Hsp40) homolog, subfamily C, member 10
Identifiers
Symbols	DNAJC10; DKFZp434J1813; ERdj5; JPDI; MGC104194
External IDs	OMIM: 607987 MGI: 1914111 HomoloGene: 10358 GeneCards: DNAJC10 Gene
Gene Ontology Molecular function • ATPase activator activity • protein binding • electron carrier activity • protein disulfide oxidoreductase activity • disulfide oxidoreductase activity • heat shock protein binding • unfolded protein binding • chaperone binding • ATPase binding • misfolded protein binding Cellular component • extracellular region • endoplasmic reticulum • endoplasmic reticulum lumen • microsome • endoplasmic reticulum chaperone complex Biological process • negative regulation of protein phosphorylation • protein folding • glycerol ether metabolic process • ER-associated protein catabolic process • positive regulation of ATPase activity • response to endoplasmic reticulum stress • cell redox homeostasis • apoptosis in response to endoplasmic reticulum stress Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	54431	66861
Ensembl	ENSG00000077232	ENSMUSG00000027006
UniProt	Q8IXB1	n/a
RefSeq (mRNA)	NM_018981	NM_024181.2
RefSeq (protein)	NP_061854	NP_077143.2
Location (UCSC)	Chr 2: 183.58 – 183.65 Mb	Chr 2: 80.16 – 80.19 Mb
PubMed search	[1]	[2]

DnaJ homolog subfamily C member 10 is a protein that in humans is encoded by the DNAJC10 gene.^[1][2][3]

References

1. ^ Cunnea PM, Miranda-Vizuete A, Bertoli G, Simmen T, Damdimopoulos AE, Hermann S, Leinonen S, Huikko MP, Gustafsson JA, Sitia R, Spyrou G (Jan 2003). "ERdj5, an endoplasmic reticulum (ER)-resident protein containing DnaJ and thioredoxin domains, is expressed in secretory cells or following ER stress". J Biol Chem 278 (2): 1059–66. doi:10.1074/jbc.M206995200. PMID 12411443. 
2. ^ Hosoda A, Kimata Y, Tsuru A, Kohno K (Jan 2003). "JPDI, a novel endoplasmic reticulum-resident protein containing both a BiP-interacting J-domain and thioredoxin-like motifs". J Biol Chem 278 (4): 2669–76. doi:10.1074/jbc.M208346200. PMID 12446677. 
3. ^ "Entrez Gene: DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54431. 

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=403697. 
• Gu SH, Chen JZ, Ying K, et al. (2004). "Cloning and identification of a novel cDNA which encodes a putative protein with a DnaJ domain and a thioredoxin active motif, human macrothioredoxin.". Biochem. Genet. 41 (7-8): 245–53. doi:10.1023/A:1025510502147. PMID 14587667. 
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928. 
• Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621. 
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
• Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.