DNAJC19

DnaJ (Hsp40) homolog, subfamily C, member 19
Identifiers
Symbols	DNAJC19; Pam18; TIM14; TIMM14
External IDs	OMIM: 608977 HomoloGene: 87176 GeneCards: DNAJC19 Gene
Gene Ontology Molecular function • heat shock protein binding Cellular component • mitochondrion • mitochondrial inner membrane • membrane • integral to membrane Biological process • protein folding • protein targeting to mitochondrion • visual perception • protein transport • genitalia development • transmembrane transport Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	131118	67713
Ensembl	ENSG00000205981	ENSMUSG00000027679
UniProt	Q96DA6	n/a
RefSeq (mRNA)	NM_001190233.1	n/a
RefSeq (protein)	NP_001177162.1	n/a
Location (UCSC)	Chr 3: 180.7 – 180.71 Mb	Chr 3: 33.95 – 33.98 Mb
PubMed search	[1]	[2]

Mitochondrial import inner membrane translocase subunit TIM14 is an enzyme that in humans is encoded by the DNAJC19 gene.^[1][2]

References

1. ^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
2. ^ "Entrez Gene: DNAJC19 DnaJ (Hsp40) homolog, subfamily C, member 19". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=131118. 

Further reading

• Sparkes R, Patton D, Bernier F (2007). "Cardiac features of a novel autosomal recessive dilated cardiomyopathic syndrome due to defective importation of mitochondrial protein.". Cardiology in the young 17 (2): 215–7. doi:10.1017/S1047951107000042. PMID 17244376. 
• Davey KM, Parboosingh JS, McLeod DR, et al. (2006). "Mutation of DNAJC19, a human homologue of yeast inner mitochondrial membrane co-chaperones, causes DCMA syndrome, a novel autosomal recessive Barth syndrome-like condition.". J. Med. Genet. 43 (5): 385–93. doi:10.1136/jmg.2005.036657. PMC 2564511. PMID 16055927. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2564511. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928. 
• Mokranjac D, Sichting M, Neupert W, Hell K (2003). "Tim14, a novel key component of the import motor of the TIM23 protein translocase of mitochondria.". EMBO J. 22 (19): 4945–56. doi:10.1093/emboj/cdg485. PMC 204468. PMID 14517234. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=204468. 
• Taylor SW, Fahy E, Zhang B, et al. (2003). "Characterization of the human heart mitochondrial proteome.". Nat. Biotechnol. 21 (3): 281–6. doi:10.1038/nbt793. PMID 12592411. 
• Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=16267. 
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.