Malignant hypertension

Malignant hypertension
Malignant hypertension
Classification and external resources

Micrograph showing thrombotic microangiopathy, a histomorphologic finding seen in malignant hypertension. Kidney biopsy. PAS stain.
ICD-10 I10
ICD-9 401.0[1]
DiseasesDB 7788
eMedicine med/1107
MeSH D006974

Malignant hypertension is a complication of hypertension characterized by very elevated blood pressure, and organ damage in the eyes, brain, heart and/or kidneys. It is considered a hypertensive emergency.

The eyes may show retinal hemorrhage, or exudate. A diagnosis of malignant hypertension must show papilledema.

The brain shows manifestations of increased intracranial pressure, such as headache, vomiting, subarachnoid, and cerebral hemorrhage.

Patients will usually suffer from left ventricular dysfunction.

The kidneys will be affected, resulting in hematuria, proteinuria, and acute renal failure.

It differs from other complications of hypertension in that it is accompanied by papilledema.[2] This can be associated with hypertensive retinopathy.

Systolic and diastolic blood pressures are usually greater than 200mmHg and 140mmHg, respectively.


  1. ^ MedaPhase: Newsletter
  2. ^ "malignant hypertension" at Dorland's Medical Dictionary

See also

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