OR52W1

Olfactory receptor, family 52, subfamily W, member 1
Identifiers
Symbols	OR52W1; OR11-71; OR52W1P
External IDs	MGI: 3030526 HomoloGene: 64859 GeneCards: OR52W1 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • plasma membrane • integral to membrane Biological process • sensory perception of smell • response to stimulus Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	120787	258352
Ensembl	ENSG00000175485	ENSMUSG00000073906
UniProt	Q6IF63	n/a
RefSeq (mRNA)	NM_001005178	NM_146355.1
RefSeq (protein)	NP_001005178	NP_666467.1
Location (UCSC)	Chr 11: 6.22 – 6.22 Mb	Chr 7: 112.52 – 112.52 Mb
PubMed search	[1]	[2]

Olfactory receptor 52W1 is a protein that in humans is encoded by the OR52W1 gene.^[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[1]

See also

• Olfactory receptor

References

1. ^ ^{a b} "Entrez Gene: OR52W1 olfactory receptor, family 52, subfamily W, member 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=120787. 

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=356993. 
• Taylor TD, Noguchi H, Totoki Y, et al. (2006). "Human chromosome 11 DNA sequence and analysis including novel gene identification.". Nature 440 (7083): 497–500. doi:10.1038/nature04632. PMID 16554811. 

External links

• MeSH OR52W1+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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