OR5AS1

Olfactory receptor, family 5, subfamily AS, member 1
Identifiers
Symbols	OR5AS1; OR11-168
External IDs	MGI: 3030945 HomoloGene: 74238 GeneCards: OR5AS1 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • plasma membrane • integral to membrane Biological process • sensory perception of smell • response to stimulus Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	219447	258586
Ensembl	ENSG00000181785	ENSMUSG00000075158
UniProt	Q8N127	n/a
RefSeq (mRNA)	NM_001001921	NM_146593.2
RefSeq (protein)	NP_001001921	NP_666804.2
Location (UCSC)	Chr 11: 55.8 – 55.8 Mb	Chr 2: 86.99 – 86.99 Mb
PubMed search	[1]	[2]

Olfactory receptor 5AS1 is a protein that in humans is encoded by the OR5AS1 gene.^[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[1]

References

1. ^ ^{a b} "Entrez Gene: OR5AS1 olfactory receptor, family 5, subfamily AS, member 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=219447. 

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=356993. 

External links

• MeSH OR5AS1+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Class II
(tetrapod specific receptors)

Family 1	A1 · A2 · B1 · C1 · D2 · D4 · D5 · E1 · E2 · F1 · F2 · G1 · I1 · J1 · J2 · J4 · K1 · L1 · L3 · L4 · L6 · L8 · M1 · N1 · N2 · Q1 · S1 · S2
Family 2	A1 · A2 · A4 · A5 · A7 · A12 · A14 · A25 · A42 · AE1 · AG1 · AG2 · AJ1 · AK2 · AP1 · AT4 · B2 · B3 · B6 · B8 · B11 · C1 · C3 · D2 · D3 · F1 · F2 · G2 · G3 · G6 · H1 · H2 · J1 · J2 · J3 · K2 · L2 · L3 · L5 · L8 · L13 · M2 · M3 · M4 · M5 · M7 · S2 · T1 · T2 · T3 · T4 · T5 · T6 · T8 · T10 · T11 · T12 · T27 · T29 · T33 · T34 · T35 · V1 · V2 · W1 · W3 · W5 · Y1 · Z1
Family 3	A1 · A2 · A3 · A4
Family 4	A5 · A15 · A16 · A47 · B1 · C3 · C5 · C6 · C11 · C12 · C13 · C15 · C16 · C45 · C46 · D1 · D2 · D5 · D6 · D9 · D10 · D11 · E2  · F3 · F4 · F5 · F6 · F15 · F16 · F17 · F21 · F29 · K1 · K2 · K3 · K5 · K13 · K14 · K15 · K17 · L1 · M1 · M2 · N2 · N4 · N5 · P4 · Q3 · S1 · S2 · X1 · X2
Family 5	A1 · A2 · AC2 · AK2 · AK3 · AN1 · AP2 · AR1 · AS1 · AT1 · AU1 · AY1 · B2 · B3 · B12 · B17  · B21 · BF1 · BU1 · C1 · D13 · D14 · D16 · D18 · F1 · H1 · H2 · H6 · H14 · H15 · I1 · J2 · K1 · K2 · K3 · K4 · L1 · L2 · M1 · M3 · M8 · M9 · M10 · M11  · P2 · P3 · R1 · T1 · T2 · T3 · U1 · V1 · W2
Family 6	A2 · B1 · B2 · B3 · C1 · C2 · C3 · C4 · C6 · C65 · C68 · C70 · C74 · C75 · C76 · F1 · J1 · K2 · K3 · K6 · M1 · N1 · N2 · P1 · Q1 · S1 · T1 · V1 · X1 · Y1
Family 7	A2 · A5 · A10 · A17 · C1 · C2 · D2 · D4 · E24 · G1 · G2 · G3
Family 8	A1 · B2 · B3 · B4 · B8 · B12 · D1 · D2 · D4 · G1 · G2 · G5 · H1 · H2 · H3 · I2 · J1 · J3 · K1 · K3 · K5 · S1 · U1
Family 9	A2 · A4 · G1 · G4 · I1 · K2 · Q1 · Q2
Family 10	A2 · A3 · A4 · A5 · A6 · A7 · AD1 · AG1 · C1 · D4 · G2 · G3 · G4 · G6 · G7 · G8 · G9 · H1 · H2 · H3 · H4 · H5 · J1 · J3 · J5 · J6 · K1 · K2 · P1 · Q1 · R2 · S1 · T2 · V1 · W1 · X1 · Z1
Family 11	A1 · G2 · H1 · H4 · H6 · L1
Family 12	D2 · D3
Family 13	A1 · C2 · C3 · C4 · C5 · C8 · C9 · D1 · F1 · G1 · H1 · J1

M: OLF anat, recp sysi -