- OR4C11
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Olfactory receptor, family 4, subfamily C, member 11 Identifiers Symbols OR4C11; OR11-136; OR4C11P External IDs MGI: 3031040 HomoloGene: 81567 GeneCards: OR4C11 Gene Gene Ontology Molecular function • receptor activity
• olfactory receptor activityCellular component • plasma membrane
• integral to membraneBiological process • sensory perception of smell
• response to stimulusSources: Amigo / QuickGO RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 219429 258896 Ensembl ENSG00000172188 ENSMUSG00000062757 UniProt Q6IEV9 n/a RefSeq (mRNA) NM_001004700 NM_001001810.2 RefSeq (protein) NP_001004700 NP_001001810.2 Location (UCSC) Chr 11:
55.37 – 55.37 MbChr 2:
88.7 – 88.71 MbPubMed search [1] [2] Olfactory receptor 4C11 is a protein that in humans is encoded by the OR4C11 gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
See also
References
Further reading
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=356993.
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Class II
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- Transmembrane receptor stubs
- G protein coupled receptors
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