OR2L8

Olfactory receptor, family 2, subfamily L, member 8
Identifiers
Symbols	OR2L8;
External IDs	MGI: 3030002 HomoloGene: 115517 GeneCards: OR2L8 Gene
Gene Ontology Molecular function • molecular_function • receptor activity • olfactory receptor activity Cellular component • plasma membrane • integral to membrane Biological process • sensory perception of smell • biological_process • response to stimulus Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	391190	258937
Ensembl	ENSG00000196936	ENSMUSG00000045341
UniProt	Q8NGY9	n/a
RefSeq (mRNA)	NM_001001963	NM_146935.1
RefSeq (protein)	NP_001001963	NP_667146.1
Location (UCSC)	Chr 1: 248.11 – 248.11 Mb	Chr 16: 19.51 – 19.52 Mb
PubMed search	[1]	[2]

Olfactory receptor 2L8 is a protein that in humans is encoded by the OR2L8 gene.^[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[1]

See also

• Olfactory receptor

References

1. ^ ^{a b} "Entrez Gene: OR2L8 olfactory receptor, family 2, subfamily L, member 8". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=391190. 

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=356993. 

{== External links ==

• MeSH OR2L8+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Class II
(tetrapod specific receptors)

Family 1	A1 · A2 · B1 · C1 · D2 · D4 · D5 · E1 · E2 · F1 · F2 · G1 · I1 · J1 · J2 · J4 · K1 · L1 · L3 · L4 · L6 · L8 · M1 · N1 · N2 · Q1 · S1 · S2
Family 2	A1 · A2 · A4 · A5 · A7 · A12 · A14 · A25 · A42 · AE1 · AG1 · AG2 · AJ1 · AK2 · AP1 · AT4 · B2 · B3 · B6 · B8 · B11 · C1 · C3 · D2 · D3 · F1 · F2 · G2 · G3 · G6 · H1 · H2 · J1 · J2 · J3 · K2 · L2 · L3 · L5 · L8 · L13 · M2 · M3 · M4 · M5 · M7 · S2 · T1 · T2 · T3 · T4 · T5 · T6 · T8 · T10 · T11 · T12 · T27 · T29 · T33 · T34 · T35 · V1 · V2 · W1 · W3 · W5 · Y1 · Z1
Family 3	A1 · A2 · A3 · A4
Family 4	A5 · A15 · A16 · A47 · B1 · C3 · C5 · C6 · C11 · C12 · C13 · C15 · C16 · C45 · C46 · D1 · D2 · D5 · D6 · D9 · D10 · D11 · E2  · F3 · F4 · F5 · F6 · F15 · F16 · F17 · F21 · F29 · K1 · K2 · K3 · K5 · K13 · K14 · K15 · K17 · L1 · M1 · M2 · N2 · N4 · N5 · P4 · Q3 · S1 · S2 · X1 · X2
Family 5	A1 · A2 · AC2 · AK2 · AK3 · AN1 · AP2 · AR1 · AS1 · AT1 · AU1 · AY1 · B2 · B3 · B12 · B17  · B21 · BF1 · BU1 · C1 · D13 · D14 · D16 · D18 · F1 · H1 · H2 · H6 · H14 · H15 · I1 · J2 · K1 · K2 · K3 · K4 · L1 · L2 · M1 · M3 · M8 · M9 · M10 · M11  · P2 · P3 · R1 · T1 · T2 · T3 · U1 · V1 · W2
Family 6	A2 · B1 · B2 · B3 · C1 · C2 · C3 · C4 · C6 · C65 · C68 · C70 · C74 · C75 · C76 · F1 · J1 · K2 · K3 · K6 · M1 · N1 · N2 · P1 · Q1 · S1 · T1 · V1 · X1 · Y1
Family 7	A2 · A5 · A10 · A17 · C1 · C2 · D2 · D4 · E24 · G1 · G2 · G3
Family 8	A1 · B2 · B3 · B4 · B8 · B12 · D1 · D2 · D4 · G1 · G2 · G5 · H1 · H2 · H3 · I2 · J1 · J3 · K1 · K3 · K5 · S1 · U1
Family 9	A2 · A4 · G1 · G4 · I1 · K2 · Q1 · Q2
Family 10	A2 · A3 · A4 · A5 · A6 · A7 · AD1 · AG1 · C1 · D4 · G2 · G3 · G4 · G6 · G7 · G8 · G9 · H1 · H2 · H3 · H4 · H5 · J1 · J3 · J5 · J6 · K1 · K2 · P1 · Q1 · R2 · S1 · T2 · V1 · W1 · X1 · Z1
Family 11	A1 · G2 · H1 · H4 · H6 · L1
Family 12	D2 · D3
Family 13	A1 · C2 · C3 · C4 · C5 · C8 · C9 · D1 · F1 · G1 · H1 · J1

M: OLF anat, recp sysi -