- OR1F2
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Olfactory receptor, family 1, subfamily F, member 2 Identifiers Symbols OR1F2P; OLFMF2; OR16-3; OR1F11; OR1F2; OR1F3P; hg91 External IDs GeneCards: OR1F2P Gene Gene Ontology Molecular function • receptor activity
• olfactory receptor activityCellular component • plasma membrane
• integral to membraneBiological process • sensory perception of smell
• response to stimulusOrthologs Species Human Mouse Entrez 26184 n/a Ensembl n/a n/a UniProt n/a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) n/a n/a PubMed search [1] n/a Olfactory receptor 1F2 is a protein that in humans is encoded by the OR1F2P gene.[1][2]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[2]
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See also
References
- ^ Bernot A, Heilig R, Clepet C, Smaoui N, Da Silva C, Petit JL, Devaud C, Chiannilkulchai N, Fizames C, Samson D, Cruaud C, Caloustian C, Gyapay G, Delpech M, Weissenbach J (Oct 1998). "A transcriptional Map of the FMF region". Genomics 50 (2): 147–60. doi:10.1006/geno.1998.5313. PMID 9653642.
- ^ a b "Entrez Gene: OR1F2 olfactory receptor, family 1, subfamily F, member 2". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26184.
Further reading
- Parmentier M, Libert F, Schurmans S, et al. (1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells.". Nature 355 (6359): 453–5. doi:10.1038/355453a0. PMID 1370859.
- Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=356993.
External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Class II
(tetrapod specific receptors)Family 1Family 2A1 · A2 · A4 · A5 · A7 · A12 · A14 · A25 · A42 · AE1 · AG1 · AG2 · AJ1 · AK2 · AP1 · AT4 · B2 · B3 · B6 · B8 · B11 · C1 · C3 · D2 · D3 · F1 · F2 · G2 · G3 · G6 · H1 · H2 · J1 · J2 · J3 · K2 · L2 · L3 · L5 · L8 · L13 · M2 · M3 · M4 · M5 · M7 · S2 · T1 · T2 · T3 · T4 · T5 · T6 · T8 · T10 · T11 · T12 · T27 · T29 · T33 · T34 · T35 · V1 · V2 · W1 · W3 · W5 · Y1 · Z1
Family 3Family 4Family 5Family 6Family 7Family 8Family 9Family 10Family 11Family 12Family 13Categories:- Human proteins
- Transmembrane receptor stubs
- G protein coupled receptors
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