- OR8D1
-
Olfactory receptor, family 8, subfamily D, member 1 Identifiers Symbols OR8D1; JCG9; OR8D3; OST004; PDJ9J14 External IDs MGI: 109309 HomoloGene: 79676 GeneCards: OR8D1 Gene Gene Ontology Molecular function • receptor activity
• olfactory receptor activityCellular component • plasma membrane
• integral to membraneBiological process • sensory perception of smell
• response to stimulusSources: Amigo / QuickGO Orthologs Species Human Mouse Entrez 283159 18324 Ensembl ENSG00000196341 ENSMUSG00000047667 UniProt Q8WZ84 n/a RefSeq (mRNA) NM_001002917 NM_146783.2 RefSeq (protein) NP_001002917 NP_666994.2 Location (UCSC) Chr 11:
124.18 – 124.18 MbChr 9:
38.66 – 38.66 MbPubMed search [1] [2] Olfactory receptor 8D1 is a protein that in humans is encoded by the OR8D1 gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
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References
Further reading
- Gaudin JC, Breuils L, Haertlé T (2002). "New GPCRs from a human lingual cDNA library.". Chem. Senses 26 (9): 1157–66. doi:10.1093/chemse/26.9.1157. PMID 11705801.
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=356993.
External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Class II
(tetrapod specific receptors)Family 1Family 2A1 · A2 · A4 · A5 · A7 · A12 · A14 · A25 · A42 · AE1 · AG1 · AG2 · AJ1 · AK2 · AP1 · AT4 · B2 · B3 · B6 · B8 · B11 · C1 · C3 · D2 · D3 · F1 · F2 · G2 · G3 · G6 · H1 · H2 · J1 · J2 · J3 · K2 · L2 · L3 · L5 · L8 · L13 · M2 · M3 · M4 · M5 · M7 · S2 · T1 · T2 · T3 · T4 · T5 · T6 · T8 · T10 · T11 · T12 · T27 · T29 · T33 · T34 · T35 · V1 · V2 · W1 · W3 · W5 · Y1 · Z1
Family 3Family 4Family 5Family 6Family 7Family 8Family 9Family 10Family 11Family 12Family 13Categories:- Human proteins
- Transmembrane receptor stubs
- G protein coupled receptors
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