OR1D2

OR1D2
Olfactory receptor, family 1, subfamily D, member 2
Identifiers
Symbols OR1D2; MGC119942; MGC119943; OLFR1; OR17-4
External IDs OMIM164342 MGI3030246 HomoloGene37634 GeneCards: OR1D2 Gene
RNA expression pattern
PBB GE OR1D2 221464 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 4991 258153
Ensembl ENSG00000184166 ENSMUSG00000058275
UniProt P34982 n/a
RefSeq (mRNA) NM_002548 NM_001011851.1
RefSeq (protein) NP_002539 NP_001011851.1
Location (UCSC) Chr 17:
3 – 3 Mb
Chr 11:
74.18 – 74.18 Mb
PubMed search [1] [2]

Olfactory receptor 1D2 is a protein that in humans is encoded by the OR1D2 gene.[1][2][3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

Contents

See also

References

  1. ^ Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J, et al. (Mar 1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature 355 (6359): 453–5. doi:10.1038/355453a0. PMID 1370859. 
  2. ^ Buck L, Axel R (May 1991). "A novel multigene family may encode odorant receptors: a molecular basis for odor recognition". Cell 65 (1): 175–87. doi:10.1016/0092-8674(91)90418-X. PMID 1840504. 
  3. ^ a b "Entrez Gene: OR1D2 olfactory receptor, family 1, subfamily D, member 2". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4991. 

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.