- OR51B6
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Olfactory receptor, family 51, subfamily B, member 6 Identifiers Symbols OR51B6; HOR5'Beta6 External IDs MGI: 1341910 HomoloGene: 66459 GeneCards: OR51B6 Gene Gene Ontology Molecular function • receptor activity
• olfactory receptor activityCellular component • plasma membrane
• integral to membraneBiological process • sensory perception of smell
• response to stimulusSources: Amigo / QuickGO Orthologs Species Human Mouse Entrez 390058 18365 Ensembl ENSG00000176239 ENSMUSG00000047163 UniProt Q9H340 n/a RefSeq (mRNA) NM_001004750 NM_013616.4 RefSeq (protein) NP_001004750 NP_038644.2 Location (UCSC) Chr 11:
5.34 – 5.37 MbChr 7:
111.05 – 111.06 MbPubMed search [1] [2] Olfactory receptor 51B5 is a protein that in humans is encoded by the OR51B6 gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
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See also
References
Further reading
- Bulger M, van Doorninck JH, Saitoh N, et al. (1999). "Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes.". Proc. Natl. Acad. Sci. U.S.A. 96 (9): 5129–34. doi:10.1073/pnas.96.9.5129. PMC 21828. PMID 10220430. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=21828.
- Bulger M, Bender MA, van Doorninck JH, et al. (2001). "Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.". Proc. Natl. Acad. Sci. U.S.A. 97 (26): 14560–5. doi:10.1073/pnas.97.26.14560. PMC 18958. PMID 11121057. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=18958.
External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Class II
(tetrapod specific receptors)Family 1Family 2A1 · A2 · A4 · A5 · A7 · A12 · A14 · A25 · A42 · AE1 · AG1 · AG2 · AJ1 · AK2 · AP1 · AT4 · B2 · B3 · B6 · B8 · B11 · C1 · C3 · D2 · D3 · F1 · F2 · G2 · G3 · G6 · H1 · H2 · J1 · J2 · J3 · K2 · L2 · L3 · L5 · L8 · L13 · M2 · M3 · M4 · M5 · M7 · S2 · T1 · T2 · T3 · T4 · T5 · T6 · T8 · T10 · T11 · T12 · T27 · T29 · T33 · T34 · T35 · V1 · V2 · W1 · W3 · W5 · Y1 · Z1
Family 3Family 4Family 5Family 6Family 7Family 8Family 9Family 10Family 11Family 12Family 13Categories:- Human proteins
- Transmembrane receptor stubs
- G protein coupled receptors
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