- OR4K5
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Olfactory receptor, family 4, subfamily K, member 5 Identifiers Symbols OR4K5; OR14-16 External IDs MGI: 3030563 HomoloGene: 17167 GeneCards: OR4K5 Gene Gene Ontology Molecular function • receptor activity
• olfactory receptor activityCellular component • plasma membrane
• integral to membraneBiological process • sensory perception of smell
• response to stimulusSources: Amigo / QuickGO Orthologs Species Human Mouse Entrez 79317 258275 Ensembl ENSG00000176281 ENSMUSG00000049011 UniProt Q8NGD3 n/a RefSeq (mRNA) NM_001005483 NM_146278.1 RefSeq (protein) NP_001005483 NP_666390.1 Location (UCSC) Chr 14:
20.39 – 20.39 MbChr 14:
50.77 – 50.77 MbPubMed search [1] [2] Olfactory receptor 4K5 is a protein that in humans is encoded by the OR4K5 gene.[1][2]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[2]
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See also
References
- ^ Malnic B, Godfrey PA, Buck LB (Feb 2004). "The human olfactory receptor gene family". Proc Natl Acad Sci U S A 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=356993.
- ^ a b "Entrez Gene: OR4K5 olfactory receptor, family 4, subfamily K, member 5". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79317.
Further reading
External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Class II
(tetrapod specific receptors)Family 1Family 2A1 · A2 · A4 · A5 · A7 · A12 · A14 · A25 · A42 · AE1 · AG1 · AG2 · AJ1 · AK2 · AP1 · AT4 · B2 · B3 · B6 · B8 · B11 · C1 · C3 · D2 · D3 · F1 · F2 · G2 · G3 · G6 · H1 · H2 · J1 · J2 · J3 · K2 · L2 · L3 · L5 · L8 · L13 · M2 · M3 · M4 · M5 · M7 · S2 · T1 · T2 · T3 · T4 · T5 · T6 · T8 · T10 · T11 · T12 · T27 · T29 · T33 · T34 · T35 · V1 · V2 · W1 · W3 · W5 · Y1 · Z1
Family 3Family 4Family 5Family 6Family 7Family 8Family 9Family 10Family 11Family 12Family 13Categories:- Human proteins
- Transmembrane receptor stubs
- G protein coupled receptors
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