- OR8K3
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Olfactory receptor, family 8, subfamily K, member 3 Identifiers Symbols OR8K3; OR11-181 External IDs MGI: 3030881 HomoloGene: 51783 GeneCards: OR8K3 Gene Gene Ontology Molecular function • receptor activity
• olfactory receptor activityCellular component • plasma membrane
• integral to membraneBiological process • sensory perception of smell
• response to stimulusSources: Amigo / QuickGO Orthologs Species Human Mouse Entrez 219473 259014 Ensembl ENSG00000181689 ENSMUSG00000075196 UniProt Q8NH51 n/a RefSeq (mRNA) NM_001005202 NM_147012.1 RefSeq (protein) NP_001005202 NP_667223.1 Location (UCSC) Chr 11:
56.09 – 56.09 MbChr 2:
86.07 – 86.07 MbPubMed search [1] [2] Olfactory receptor, family 8, subfamily K, member 3, also known as OR8K3, is a protein which in humans is encoded by the OR8K3 gene.[1]
Contents
Function
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
References
- ^ a b "Entrez Gene: OR8K3 olfactory receptor, family 8, subfamily K, member 3". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=219473.; This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Further reading
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=356993.
External links
Class II
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- Transmembrane receptor stubs
- G protein coupled receptors
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