- OR1L3
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Olfactory receptor, family 1, subfamily L, member 3 Identifiers Symbols OR1L3; OR9-28; OR9-D External IDs HomoloGene: 105279 GeneCards: OR1L3 Gene Gene Ontology Molecular function • receptor activity
• olfactory receptor activityCellular component • plasma membrane
• integral to membraneBiological process • sensory perception of smell
• response to stimulusSources: Amigo / QuickGO RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 26735 n/a Ensembl ENSG00000171481 n/a UniProt Q8NH93 n/a RefSeq (mRNA) NM_001005234 n/a RefSeq (protein) NP_001005234 n/a Location (UCSC) Chr 9:
125.44 – 125.44 Mbn/a PubMed search [1] n/a Olfactory receptor 1L3 is a protein that in humans is encoded by the OR1L3 gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
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References
Further reading
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=356993.
- Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9.". Nature 429 (6990): 369–74. doi:10.1038/nature02465. PMC 2734081. PMID 15164053. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2734081.
External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Class II
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- Transmembrane receptor stubs
- G protein coupled receptors
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