- OR2AG1
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Olfactory receptor, family 2, subfamily AG, member 1 Identifiers Symbols OR2AG1; OR11-79; OR2AG3 External IDs MGI: 3030539 HomoloGene: 12558 GeneCards: OR2AG1 Gene Gene Ontology Molecular function • receptor activity
• olfactory receptor activityCellular component • plasma membrane
• integral to membraneBiological process • sensory perception of smell
• response to stimulusSources: Amigo / QuickGO RNA expression pattern 
More reference expression data Orthologs Species Human Mouse Entrez 144125 259034 Ensembl ENSG00000170803 ENSMUSG00000047120 UniProt Q9H205 n/a RefSeq (mRNA) NM_001004489 NM_147032.2 RefSeq (protein) NP_001004489 NP_667243.2 Location (UCSC) Chr 11:
6.81 – 6.81 MbChr 7:
114.02 – 114.02 MbPubMed search [1] [2] Olfactory receptor 2AG1 is a protein that in humans is encoded by the OR2AG1 gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
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References
Further reading
- Lane RP, Cutforth T, Young J, et al. (2001). "Genomic analysis of orthologous mouse and human olfactory receptor loci.". Proc. Natl. Acad. Sci. U.S.A. 98 (13): 7390–5. doi:10.1073/pnas.131215398. PMC 34679. PMID 11416212. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=34679.
- Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=356993.
- Neuhaus EM, Mashukova A, Zhang W, et al. (2006). "A specific heat shock protein enhances the expression of mammalian olfactory receptor proteins.". Chem. Senses 31 (5): 445–52. doi:10.1093/chemse/bjj049. PMID 16565291.
- Mashukova A, Spehr M, Hatt H, Neuhaus EM (2006). "Beta-arrestin2-mediated internalization of mammalian odorant receptors.". J. Neurosci. 26 (39): 9902–12. doi:10.1523/JNEUROSCI.2897-06.2006. PMID 17005854.
External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Class II
(tetrapod specific receptors)Family 1Family 2A1 · A2 · A4 · A5 · A7 · A12 · A14 · A25 · A42 · AE1 · AG1 · AG2 · AJ1 · AK2 · AP1 · AT4 · B2 · B3 · B6 · B8 · B11 · C1 · C3 · D2 · D3 · F1 · F2 · G2 · G3 · G6 · H1 · H2 · J1 · J2 · J3 · K2 · L2 · L3 · L5 · L8 · L13 · M2 · M3 · M4 · M5 · M7 · S2 · T1 · T2 · T3 · T4 · T5 · T6 · T8 · T10 · T11 · T12 · T27 · T29 · T33 · T34 · T35 · V1 · V2 · W1 · W3 · W5 · Y1 · Z1
Family 3Family 4Family 5Family 6Family 7Family 8Family 9Family 10Family 11Family 12Family 13Categories:- Human proteins
- Transmembrane receptor stubs
- G protein coupled receptors
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