- OR13C8
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Olfactory receptor, family 13, subfamily C, member 8 Identifiers Symbols OR13C8; OR37H; OR9-10 External IDs MGI: 3030106 HomoloGene: 17409 GeneCards: OR13C8 Gene Gene Ontology Molecular function • receptor activity
• olfactory receptor activityCellular component • plasma membrane
• integral to membraneBiological process • sensory perception of smell
• response to stimulusSources: Amigo / QuickGO RNA expression pattern 
More reference expression data Orthologs Species Human Mouse Entrez 138802 258836 Ensembl ENSG00000186943 ENSMUSG00000051593 UniProt Q8NGS7 n/a RefSeq (mRNA) NM_001004483 NM_146839.1 RefSeq (protein) NP_001004483 NP_667050.1 Location (UCSC) Chr 9:
107.33 – 107.33 MbChr 4:
52.92 – 52.93 MbPubMed search [1] [2] Olfactory receptor 13C8 is a protein that in humans is encoded by the OR13C8 gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
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References
Further reading
- Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
- Hoppe R, Breer H, Strotmann J (2004). "Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human.". Genomics 82 (3): 355–64. doi:10.1016/S0888-7543(03)00116-2. PMID 12906860.
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=356993.
- Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9.". Nature 429 (6990): 369–74. doi:10.1038/nature02465. PMC 2734081. PMID 15164053. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2734081.
External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Class II
(tetrapod specific receptors)Family 1Family 2A1 · A2 · A4 · A5 · A7 · A12 · A14 · A25 · A42 · AE1 · AG1 · AG2 · AJ1 · AK2 · AP1 · AT4 · B2 · B3 · B6 · B8 · B11 · C1 · C3 · D2 · D3 · F1 · F2 · G2 · G3 · G6 · H1 · H2 · J1 · J2 · J3 · K2 · L2 · L3 · L5 · L8 · L13 · M2 · M3 · M4 · M5 · M7 · S2 · T1 · T2 · T3 · T4 · T5 · T6 · T8 · T10 · T11 · T12 · T27 · T29 · T33 · T34 · T35 · V1 · V2 · W1 · W3 · W5 · Y1 · Z1
Family 3Family 4Family 5Family 6Family 7Family 8Family 9Family 10Family 11Family 12Family 13Categories:- Human proteins
- Transmembrane receptor stubs
- G protein coupled receptors
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