Neural proliferation, differentiation and control, 1
Symbols NPDC1; CAB; CAB-; CAB-1; CAB1; DKFZp586J0523; NPDC-1
External IDs OMIM605798 MGI1099802 HomoloGene32050 GeneCards: NPDC1 Gene
RNA expression pattern
PBB GE NPDC1 218086 at tn.png
More reference expression data
Species Human Mouse
Entrez 56654 18146
Ensembl ENSG00000107281 ENSMUSG00000015094
UniProt Q9NQX5 Q925Q2
RefSeq (mRNA) NM_015392 NM_008721.3
RefSeq (protein) NP_056207 NP_032747.2
Location (UCSC) Chr 9:
139.93 – 139.94 Mb
Chr 2:
25.25 – 25.27 Mb
PubMed search [1] [2]

Neural proliferation differentiation and control protein 1 is a protein that in humans is encoded by the NPDC1 gene.[1][2]


NPDC1 has been shown to interact with E2F1.[3]


  1. ^ Qu X, Zhang C, Zhai Y, Xing G, Wei H, Yu Y, Wu S, He F (Mar 2001). "Characterization and tissue expression of a novel human gene npdc1". Gene 264 (1): 37–44. doi:10.1016/S0378-1119(01)00324-9. PMID 11245976. 
  2. ^ "Entrez Gene: NPDC1 neural proliferation, differentiation and control, 1". 
  3. ^ Sansal, I; Dupont E, Toru D, Evrard C, Rouget P (Oct. 2000). "NPDC-1, a regulator of neural cell proliferation and differentiation, interacts with E2F-1, reduces its binding to DNA and modulates its transcriptional activity". Oncogene (ENGLAND) 19 (43): 5000–9. doi:10.1038/sj.onc.1203843. ISSN 0950-9232. PMID 11042687. 

Further reading

Wikimedia Foundation. 2010.

Игры ⚽ Нужен реферат?

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”