- Midecamycin
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Midecamycin Systematic (IUPAC) name (2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-4-(dimethylamino)-5-hydroxy-6-{[(4R,6S,7R,9R,10R,11E,13E,16R)-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-4-(propanoyloxy)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy}-2-methyloxan-3-yl]oxy}-4-hydroxy-2,4-dimethyloxan-3-yl propanoate Clinical data AHFS/Drugs.com International Drug Names Pregnancy cat. ? Legal status ? Identifiers CAS number 35457-80-8 ATC code J01FA03 PubChem CID 5382853 ChemSpider 4445365 UNII N34Z0Y5UH7 KEGG D01339 Chemical data Formula C41H67NO15 Mol. mass 813.968 g/mol SMILES eMolecules & PubChem - InChI=1S/C41H67NO15/c1-11-30(45)54-29-21-32(47)51-24(4)16-14-13-15-17-28(44)23(3)20-27(18-19-43)37(38(29)50-10)57-40-35(48)34(42(8)9)36(25(5)53-40)56-33-22-41(7,49)39(26(6)52-33)55-31(46)12-2/h13-15,17,19,23-29,33-40,44,48-49H,11-12,16,18,20-22H2,1-10H3/b14-13+,17-15+/t23-,24-,25-,26+,27+,28+,29-,33+,34-,35-,36-,37+,38+,39+,40+,41-/m1/s1
Key:DMUAPQTXSSNEDD-QALJCMCCSA-N
Physical data Melt. point 155–156 °C (311–313 °F) Solubility in water Soluble in acidic/low pH water; Very soluble in methanol, chloroform, ethyl acetate, benzene, ethyl ether; Almost completely in ethanol(>95.5) mg/mL (20 °C) (what is this?) (verify) Midecamycin is a macrolide antibiotic. Synthesized from Streptomyces mycarofaciens.
Physical Properties
Melting point vary depending on the compound type. It may also vary depending on the source consulted. Example:
For the A1 type:
The Merck Index reports 155-156 Celsius. The Japanese Pharmacopoeia reports 153–158 Celsius.
For the A3 type:
The Merck Index reports 122-125 Celsius.
Antibacterials: protein synthesis inhibitors (J01A, J01B, J01F, J01G, QJ01XQ) 30S -mycin (Streptomyces)Neomycin# (Framycetin, Paromomycin, Ribostamycin)
Kanamycin# (Amikacin, Arbekacin, Bekanamycin, Dibekacin, Tobramycin)
Paromomycin-micin (Micromonospora)Tetracyclines50S Linezolid • Torezolid • Eperezolid • Posizolid • RadezolidPleuromutilinsRetapamulin • Tiamulin • ValnemulinErythromycin# • Azithromycin# • Spiramycin • Midecamycin • Oleandomycin • Roxithromycin • Josamycin • Troleandomycin • Clarithromycin • Miocamycin • Rokitamycin • Dirithromycin • Flurithromycin • Ketolide (Telithromycin, Cethromycin, Solithromycin)EF-G Steroid antibacterialsThis systemic antibacterial-related article is a stub. You can help Wikipedia by expanding it. - InChI=1S/C41H67NO15/c1-11-30(45)54-29-21-32(47)51-24(4)16-14-13-15-17-28(44)23(3)20-27(18-19-43)37(38(29)50-10)57-40-35(48)34(42(8)9)36(25(5)53-40)56-33-22-41(7,49)39(26(6)52-33)55-31(46)12-2/h13-15,17,19,23-29,33-40,44,48-49H,11-12,16,18,20-22H2,1-10H3/b14-13+,17-15+/t23-,24-,25-,26+,27+,28+,29-,33+,34-,35-,36-,37+,38+,39+,40+,41-/m1/s1