Pyrophosphomevalonate decarboxylase

Pyrophosphomevalonate decarboxylase: mevalonate (diphospho) decarboxylase

Identifiers

Symbol MVD

Entrez 4597

HUGO 7529

OMIM 603236

RefSeq NM_002461

UniProt P53602

Other data

EC number 4.1.1.33

Locus Chr. 16 q24.3

Pyrophosphomevalonate decarboxylase (or mevalonate-5-pyrophosphate decarboxylase) is an enzyme in the mevalonate pathway.

Mevalonate pathway

External links

MeSH Pyrophosphomevalonate+decarboxylase

v · d · eCarbon-carbon lyases (EC 4.1)

4.1.1: Carboxy-lyases
Pyruvate decarboxylase · Oxaloacetate decarboxylase · Acetoacetate decarboxylase · Malonyl-CoA decarboxylase · Glutamate decarboxylase · Ornithine decarboxylase · Lysine decarboxylase · Phosphoribosylaminoimidazole carboxylase · Histidine decarboxylase · Uridine monophosphate synthetase/Orotidine 5'-phosphate decarboxylase · Aromatic L-amino acid decarboxylase · Phosphoenolpyruvate carboxylase · Pyrophosphomevalonate decarboxylase · Uroporphyrinogen III decarboxylase · RuBisCO · Phosphoenolpyruvate carboxykinase · Adenosylmethionine decarboxylase

4.1.2: Aldehyde-lyases
Aldolase (Aldolase A, Aldolase B, Aldolase C) · 2-hydroxyphytanoyl-CoA lyase · Threonine aldolase

4.1.3: Oxo-acid-lyases
3-hydroxy-3-methylglutaryl-CoA lyase

4.1.99: Other
Tryptophanase

B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6

v · Metabolism: lipid metabolism · ketones/cholesterol synthesis enzymes/steroid metabolism

Mevalonate pathway

To HMG-CoA

Acetyl-Coenzyme A acetyltransferase · HMG-CoA synthase (regulated step)

Ketogenesis

HMG-CoA lyase · 3-hydroxybutyrate dehydrogenase · Thiophorase

To Mevalonic acid

HMG-CoA reductase

To DMAPP

Mevalonate kinase · Phosphomevalonate kinase · Pyrophosphomevalonate decarboxylase · Isopentenyl-diphosphate delta isomerase

Geranyl-

Dimethylallyltranstransferase · Geranyl pyrophosphate

To cholesterol

To lanosterol

Farnesyl-diphosphate farnesyltransferase · Squalene monooxygenase · Lanosterol synthase

7-Dehydrocholesterol path

Lanosterol 14α-demethylase · Sterol-C5-desaturase-like · 7-Dehydrocholesterol reductase

Desmosterol path

24-dehydrocholesterol reductase

To Bile acids
Cholesterol 7α-hydroxylase · Sterol 27-hydroxylase

Steroidogenesis

To pregnenolone

Side-chain cleavage

To corticosteroids

aldosterone: 18-hydroxylase

cortisol/cortisone: 17α-hydroxylase · 11β dehydrogenase (HSD11B1, HSD11B2)
both: 3β dehydrogenase · 21α-hydroxylase · 11β-hydroxylase

To sex hormones

To androgens

17α-hydroxylase/17,20 lyase · 3β dehydrogenase · 17β dehydrogenase · 5α reductase (1,2)

To estrogens

Aromatase

Other/ungrouped

Steroid metabolism: sulfatase (Steroid sulfatase) · sulfotransferase (SULT1A1, SULT2A1)
Steroidogenic acute regulatory protein

M: MET

mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m

k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon

m(A16/C10),i(k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)

M: END

anat/phys/devp/horm

noco(d)/cong/tumr, sysi/epon

proc, drug (A10/H1/H2/H3/H5)

Categories:
Genes on chromosome 16
Biochemistry stubs

mevalonate (diphospho) decarboxylase
Identifiers
Symbol	MVD
Entrez	4597
HUGO	7529
OMIM	603236
RefSeq	NM_002461
UniProt	P53602
Other data
EC number	4.1.1.33
Locus	Chr. 16 q24.3

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Look at other dictionaries:

Diphosphomevalonate decarboxylase — Identifiers EC number 4.1.1.33 CAS number 9024 66 2 … Wikipedia
Orotidine 5'-phosphate decarboxylase — E. coli OMP decarboxylase.[1] Identifiers EC number … Wikipedia
Ornithine decarboxylase — Identifiers EC number 4.1.1.17 CAS number 9024 60 6 … Wikipedia
Aromatic L-amino acid decarboxylase — Ribbon diagram of a domestic pig DOPA decarboxylase dimer.[1] … Wikipedia
Malonyl-CoA decarboxylase — Identifiers EC number 4.1.1.9 CAS number 9024 99 1 … Wikipedia
Ornithine decarboxylase antizyme — is a ornithine decarboxylase inhibitor. It was first characterized in 1981.[1] The genes include OAZ1, OAZ2, and OAZ3. References ^ … Wikipedia
Oxaloacetate decarboxylase — Identifiers EC number 4.1.1.3 CAS number 9024 98 0 … Wikipedia
Carboxy-lyases — Carboxy lyases, also known as decarboxylases, are carbon–carbon lyases that add or remove a carboxyl group from organic compounds. These enzymes catalyze the decarboxylation of amino acids, beta keto acids and alpha keto acids[1]. Contents 1… … Wikipedia
Phosphoenolpyruvate carboxylase — Identifiers EC number 4.1.1.31 CAS number 9067 77 0 … Wikipedia
Phosphoenolpyruvate carboxykinase — Not to be confused with Phosphoenolpyruvate carboxylase. Phosphoenolpyruvate carboxykinase PDB rendering based on 1khb. Identifiers Symbol … Wikipedia

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Pyrophosphomevalonate decarboxylase

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Pyrophosphomevalonate decarboxylase

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