- Schwannoma
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Schwannoma Classification and external resources
SchwannomaICD-10 C72.4 ICD-9 225.1 ICD-O: M9560/0 DiseasesDB 33713 MeSH D009442 A schwannoma (also known as an "acoustic neuroma,"[1] "neurilemmoma,"[2]:621 "neurinoma,"[1] "neurolemmoma,"[1] and "Schwann cell tumor"[1]) is a benign nerve sheath tumor composed of Schwann cells, which normally produce the insulating myelin sheath covering peripheral nerves.
Schwannomas are very homogeneous tumors, consisting only of Schwann cells. The tumor cells always stay on the outside of the nerve, but the tumor itself may either push the nerve aside and/or up against a bony structure (thereby possibly causing damage). Schwannomas are relatively slow growing. For reasons not yet understood, schwannomas are mostly benign and less than 1% become malignant, degenerating into a form of cancer known as neurofibrosarcoma.
Schwannomas can arise from a genetic disorder called neurofibromatosis. They are universally S-100 positive.
Schwannomas can be removed surgically, but can then recur.
Contents
See also
- Intranodal palisaded myofibroblastoma
Additional images
References
- ^ a b c d Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.
- ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
See also
- Neurofibroma
- Vestibular schwannoma (Acoustic neuroma)
Nervous tissue tumors/NS neoplasm/Neuroectodermal tumor (ICD-O 9350–9589) (C70–C72, D32–D33, 191–192/225) Endocrine/
sellar (9350–9379)other: PinealomaCNS
(9380–9539)Astrocytoma (Pilocytic astrocytoma, Pleomorphic xanthoastrocytoma, Fibrillary (also diffuse or lowgrade) astrocytomas, Anaplastic astrocytoma, Glioblastoma multiforme)Ependymoma · SubependymomaMultiple/unknownMature
neuronNeuroblastoma (Esthesioneuroblastoma, Ganglioneuroblastoma) · Medulloblastoma · Atypical teratoid rhabdoid tumorPrimitiveMeningiomas
(meninges)HematopoieticPNS: NST
(9540–9579)cranial and paraspinal nerves: Neurofibroma (Neurofibrosarcoma, Neurofibromatosis) · Neurilemmoma/Schwannoma (Acoustic neuroma) · Malignant peripheral nerve sheath tumornote: not all brain tumors are of nervous tissue, and not all nervous tissue tumors are in the brain (see brain metastases)
Categories:- Disease stubs
- PNS neoplasia
- Dermal and subcutaneous growths
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