- Ependyma
Infobox Anatomy
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Caption = Section of central canal of medulla spinalis, showing ependymal and neuroglial cells.
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MeshNumber = A08.186.211.276.460Ependyma is the thin epithelial membrane lining the
ventricular system of thebrain and thespinal cord . Ependyma is one of the four types ofneuroglia in thecentral nervous system . It is involved in the production ofcerebrospinal fluid (CSF).Ependymal Cells
The ependyma is made up of ependymal cells. These are the
epithelial cells that line the CSF-filled ventricles in the brain and thecentral canal of the spinal cord. The cells are cuboidal/columnar. Theirapical surfaces are covered in a layer ofcilia , which circulate CSF around the central nervous system. Their apical surfaces are also covered withmicrovilli , which absorb CSF. Within the brain's ventricles, a population of modified ependymal cells and capillaries together form a system called thechoroid plexus , which produces the CSF.They are also Glial cells and CSF producing cells.Pathology
Ependymoma is a tumor of the ependyma. Inflammation of ependymal cells, or ependymitis, is a hallmark pathology of tertiary syphilitic infections.
tem cells
Jonas Frisén and his colleagues at the
Karolinska Institute inStockholm believe that ependyma is the prime candidate for the location of neuralstem cells . [cite journal | author = Johansson CB, Momma S, Clarke DL, Risling M, Lendahl U, Frisen J | title = Identification of a neural stem cell in the adult mammalian central nervous system | journal = Cell | volume = 96 | issue = 1 | pages = 25–34 | year = 1999 | pmid = 9989494 | doi = 10.1016/S0092-8674(00)80956-3]References
External links
* [http://missinglink.ucsf.edu/lm/ids_104_cns_injury/Response%20_to_Injury/EpendymalCells.htm Illustrations at ucsf.edu]
* [http://synapses.mcg.edu/atlas/2_2intro.stm Atlas at ]
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