Indecainide

Indecainide: Indecainide

Systematic (IUPAC) name

9-[3-(isopropylamino)propyl]-9H-fluorene-9-carboxamide

Clinical data

Pregnancy cat. ?

Legal status ?

Identifiers

CAS number 74517-78-5^Y 73681-12-6 (HCl)

ATC code None

PubChem CID 52194

DrugBank DB00192

ChemSpider 47194^Y

UNII 3AZF20DM1T^Y

KEGG D04521^Y

ChEMBL CHEMBL1201242^N

Chemical data

Formula C₂₀H₂₄N₂O

Mol. mass 308.42 g/mol

SMILES eMolecules & PubChem

InChI

InChI=1S/C20H24N2O/c1-14(2)22-13-7-12-20(19(21)23)17-10-5-3-8-15(17)16-9-4-6-11-18(16)20/h3-6,8-11,14,22H,7,12-13H2,1-2H3,(H2,21,23)^Y
Key:UCEWGESNIULAGX-UHFFFAOYSA-N^Y

N(what is this?) (verify)

Indecainide (INN, trade name Decabid) is a class 1c antiarrhythmic agent. Developed and marketed by Lilly it has now been discontinued.

External links

FDA drug details [1]

v · d · eAntiarrhythmic agents (C01B)

Channel blockers

class I
(Na⁺ channel blockers)

class Ia (Phase 0→ and Phase 3→)

Procainamide # • Quinidine # • Ajmaline • Disopyramide • Prajmaline • Lorajmine • Sparteine

class Ib (Phase 3←)

IV (Lidocaine #) • enteral (Mexiletine, Tocainide, Aprindine)

class Ic (Phase 0→)

Encainide • Flecainide • Lorcainide • Moricizine‡ • Propafenone

class III
(Phase 3→, K⁺ channel blockers)

Amiodarone • Dronedarone • Bretylium • Bunaftine • Dofetilide • Ibutilide • Nifekalant • Sotalol • Tedisamil • Vernakalant • E-4031

class IV
(Phase 4→, Ca²⁺ channel blockers)

Verapamil # • Diltiazem

Receptor agonists
and antagonists

class II
(Phase 4→, β blockers)

Propranolol • Nadolol • Pindolol • cardioselective (Atenolol, Metoprolol, Acebutolol, Esmolol)

A1 agonist

Adenosine

M2

muscarinic antagonist: Atropine • Quinidine • Disopyramide
muscarinic agonist: Digoxin

α receptors

Quinidine • Verapamil • Amiodarone • Bretylium

Ion transporters

Na⁺ / K⁺-ATPase

Digoxin

^#WHO-EM. ^‡Withdrawn from market. Clinical trials: ^†Phase III. ^§Never to phase III

M: HRT

anat/phys/devp

noco/cong/tumr, sysi/epon, injr

proc, drug (C1A/1B/1C/1D), blte

This drug article relating to the cardiovascular system is a stub. You can help Wikipedia by expanding it.

Academic Dictionaries and Encyclopedias

Indecainide

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Systematic (IUPAC) name
9-[3-(isopropylamino)propyl]-9H-fluorene-9-carboxamide
Clinical data
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	74517-78-5^Y 73681-12-6 (HCl)
ATC code	None
PubChem	CID 52194
DrugBank	DB00192
ChemSpider	47194^Y
UNII	3AZF20DM1T^Y
KEGG	D04521^Y
ChEMBL	CHEMBL1201242^N
Chemical data
Formula	C₂₀H₂₄N₂O
Mol. mass	308.42 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C20H24N2O/c1-14(2)22-13-7-12-20(19(21)23)17-10-5-3-8-15(17)16-9-4-6-11-18(16)20/h3-6,8-11,14,22H,7,12-13H2,1-2H3,(H2,21,23)^Y Key:UCEWGESNIULAGX-UHFFFAOYSA-N^Y
N(what is this?) (verify)

Academic Dictionaries and Encyclopedias

Wikipedia

Indecainide

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