Lorcainide

Lorcainide

drugbox
IUPAC_name = "N"-(4-chlorophenyl)-2-phenyl-"N"-(1-propan-2-yl-
4-piperidyl)acetamide


CAS_number = 59729-31-6
ATC_prefix = C01
ATC_suffix = BC07
PubChem = 42884
DrugBank =
C = 22 | H = 27 | Cl = 1 | N = 2 | O = 1
molecular_weight = 370.915 g/mol
bioavailability =
protein_bound = 78
metabolism =
elimination_half-life = 14.3 +/-3.7
excretion =
pregnancy_AU =
pregnancy_US =
pregnancy_category =
legal_AU =
legal_UK =
legal_US =
legal_status =
routes_of_administration =

Lorcainide is a class 1c antiarrhythmic agent. It was discovered at Janssen Pharmaceutica in 1968.

References

* Kesteloot H, Stroobandt R., Clinical experience with lorcainide (R 15 889), a new anti-arrhythmic drug, Arch Int Pharmacodyn Ther. 1977 Dec;230(2):225-34.
* Carmeliet E, Janssen PA, Marsboom R, Van Nueten JM, Xhonneux R., Antiarrhythmic, electrophysiologic and hemodynamic effects of lorcainide, Arch Int Pharmacodyn Ther. 1978 Jan;231(1):104-30.


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