Tedisamil

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IUPACName=3,7-bis(cyclopropylmethyl)spiro [3,7-diazabicyclo [3.3.1] nonane-9,1'-cyclopentane]
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Section1= Chembox Identifiers
CASNo=90961-53-8
PubChem=65825
SMILES=C1CCC2(C1)C3CN(CC2CN(C3)CC4CC4)CC5CC5
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Formula=C₁₉H₃₂N₂
MolarMass=288.470 g/mol
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Tedisamil (planned trade name Pulzium) is an investigational drug for atrial fibrillation and atrial flutter. It is currently being developed by Solvay and is currently under regulatory review by the United States Food and Drug Administration.

On April 25, 2007, Solvay submitted a New Drug Application for tedisamil, and on December 12, 2007, the Cardio-Renal Advisory Committee of the FDA voted against approval of tedisamil, at this time, requesting that Solvay Pharmaceuticals provides additional information to the FDA. [cite web |url=http://www.drugs.com/nda/pulzium_071213.html |title=Drugs.com, Solvay Pharmaceuticals, Inc. Responds to Advisory Committee Recommendation for Further Study of Tedisamil to Treat Atrial Fibrillation |accessdate=2008-03-15 |format= |work= ]

References