Ajmaline

Ajmaline

drugbox
IUPAC_name = (17"R",21β)-ajmalan-17,21-diol


CAS_number = 4360-12-7
ATC_prefix = C01
ATC_suffix = BA05
PubChem = 20367
DrugBank =
C = 20 | H = 26 | N = 2 | O = 2
molecular_weight = 326.433 g/mol
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Ajmaline is a class Ia antiarrhythmic agent. It is often used to bring out typical findings of ST elevations in patients suspected of having Brugada syndrome.

The compound was first isolated by Salimuzzaman Siddiqui in 1931 [Siddiqui, S.; Siddiqui, R. H. (1931). "J. Indian Chem. Soc." 8: 667–80.] from the roots of "Rauwolfia serpentina". He named it Ajmaline, after Hakim Ajmal Khan, one of the most illustrious practitioners of Unani medicine in South Asia.Ahmed Nasim Sandilvi (2003), [http://www.dawn.com/weekly/science/archive/030412/science5.htm Salimuzzaman Siddiqui: pioneer of scientific research in Pakistan] . Daily Dawn. 12 April, 2003. Retrieved on 19 July 2007.]

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Look at other dictionaries:

  • Ajmaline — Général No CAS …   Wikipédia en Français

  • ajmaline — ● ajmaline nom féminin Alcaloïde isolé des racines de Rauwolfia serpentina, utilisé dans le traitement des troubles cardiaques …   Encyclopédie Universelle

  • ajmaline — indinė rauvolfija statusas T sritis vardynas apibrėžtis Stepukinių šeimos vaistinis augalas (Rauvolfia serpentina), paplitęs atogrąžų Azijoje. atitikmenys: lot. Rauvolfia serpentina angl. ajmaline; rauwolfia; serpentine wood; snakewood šaltinis… …   Lithuanian dictionary (lietuvių žodynas)

  • ajmaline — noun An antiarrhythmic drug originally isolated from the roots of Rauwolfia serpentina …   Wiktionary

  • ajmaline — An indole alkaloid from the roots of Rauwolfia serpentina, related to reserpine, serpentine, and yohimbine; has been used for treatment of hypertension and as a tranquilizer or sedative …   Medical dictionary

  • ajmaline — aj·ma·line …   English syllables

  • ajmaline — ˈajməˌlēn noun ( s) Etymology: origin unknown : an amber crystalline alkaloid C20H26N2O2 obtained from trees or shrubs of the genus Rauwolfia, especially from an Asiatic shrub (R. serpentina) …   Useful english dictionary

  • 4360-12-7 — Ajmaline Ajmaline Général No CAS …   Wikipédia en Français

  • Индольные алкалоиды — Структурная формула индола Индольные алкалоиды  класс алкалоидов, содержащих в своей структуре ядро индола или его производных …   Википедия

  • Ajmalan — is a parent hydride used in the IUPAC nomenclature of natural products and also in CAS nomenclature.International Union of Pure and Applied Chemistry (1999). [http://old.iupac.org/publications/pac/1999/pdf/7104x0587.pdf Revised Section F: Natural …   Wikipedia

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