Corneal limbus

Corneal limbus
Corneal limbus
Limbus.png
Schematic diagram of the human eye.
Latin limbus corneae

The corneal limbus is the border of the cornea and the sclera (the white of the eye). The limbus is a common site for the occurrence of corneal epithelial neoplasm. The Limbus contains radially oriented fibrovascular ridges known as the palisades of Vogt that may harbour a stem cell population.[1] The palisades of Vogt are more common in the superior and inferior quadrants around the eye.[2] Aniridia, a developmental anomaly of the iris, disrupts the normal barrier of the cornea to the conjunctival epithelial cells at the limbus.

References

  1. ^ Thomas PB, Liu YH, Zhuang FF, Selvam S, Song SW, Smith RE, Trousdale MD, Yiu SC (2007). "Identification of Notch-1 expression in the limbal basal epithelium". Mol. Vis. 13: 337–44. PMC 2633467. PMID 17392684. http://www.molvis.org/molvis/v13/a37/. 
  2. ^ Goldberg MF, Bron AJ (1982). "Limbal palisades of Vogt". Trans Am Ophthalmol Soc 80: 155–71. PMC 1312261. PMID 7182957. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1312261. 

External links

v · d · eSensory system – visual system – globe of eye (TA A15.2.1–6, TH 3.11.08.0-5, GA 10.1005)
Fibrous tunic (outer)
Episcleral layer • Schlemm's canal • Trabecular meshwork
1: posterior compartment 2: ora serrata 3: ciliary muscle 4: ciliary zonules 5: canal of Schlemm 6: pupil 7: anterior chamber 8: cornea 9: iris 10: lens cortex 11: lens nucleus 12: ciliary process 13: conjunctiva 14: inferior oblique muscule 15: inferior rectus muscule 16: medial rectus muscle 17: retinal arteries and veins 18: optic disc 19: dura mater 20: central retinal artery 21: central retinal vein 22: optical nerve 23: vorticose vein 24: bulbar sheath 25: macula 26: fovea 27: sclera 28: choroid 29: superior rectus muscle 30: retina1:posterior compartment 2:ora serrata 3:ciliary muscle 4:ciliary zonules 5:canal of Schlemm 6:pupil 7:anterior chamber 8:cornea 9:iris 10:lens cortex 11:lens nucleus 12:ciliary process 13:conjunctiva 14:inferior oblique muscule 15:inferior rectus muscule 16:medial rectus muscle 17:retinal arteries and veins 18:optic disc 19:dura mater 20:central retinal artery 21:central retinal vein 22:optical nerve 23:vorticose vein 24:bulbar sheath 25:macula 26:fovea 27:sclera 28:choroid 29:superior rectus muscle 30:retina
About this image
Uvea/vascular tunic (middle)
Retina (inner)
Layers
Cells
Photoreceptor cells (Cone cell, Rod cell) → (Horizontal cell) → Bipolar cell → (Amacrine cell) → Retina ganglion cell (Midget cell, Parasol cell, Bistratified cell, Giant retina ganglion cells, Photosensitive ganglion cell) → Diencephalon: P cell, M cell, K cell
Muller glia
Other
Macula (Foveola, Fovea centralis) • Optic disc (Optic cup)
Anterior segment
Anterior chamber • Aqueous humour • Posterior chamber • Lens (Capsule of lens, Zonule of Zinn)
Posterior segment
Other

M: EYE

anat(g/a/p)/phys/devp/prot

noco/cong/tumr, epon

proc, drug(S1A/1E/1F/1L)



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