- Schlemm's canal
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Caption = Enlarged general view of the iridial angle. (Labeled with older label of 'sinus venosus scleræ' at center top.)
Caption2 = The upper half of a sagittal section through the front of the
eyeball. (Canal of Schlemm labeled at center left.)
Schlemm's canal, also known as canal of Schlemm or the scleral venous sinus, is a circular channel in the
eyethat collects aqueous humorfrom the anterior chamberand delivers it into the bloodstream. [Cassin, B. and Solomon, S. "Dictionary of Eye Terminology". Gainsville, Florida: Triad Publishing Company, 1990.]
The canal is essentially an endothelium-lined tube, resembling that of a lymphatic vessel. On the inside of the canal, nearest to the aqueous humor, it is covered by the
trabecular meshwork, this region makes the greatest contribution to outflow resistance of the aqueous humor.
Friedrich Schlemm(1795-1858), a German anatomist.
Role in glaucoma
The canal transfers approximately 2-3 microliters of aqueous humor per minute. [Johnson MC, Kamm RD. [http://www.iovs.org/cgi/reprint/24/3/320.pdf "The role of Schlemm's canal in aqueous outflow from the human eye."] "Invest Ophthalmol Vis Sci." 1983 Mar;24(3):320-5. PMID 6832907.] If debris builds up, due to infection or injury in the aqueous humor, the canal is blocked and
glaucomais the result.
Canaloplasty is an advanced, nonpenetrating procedure designed to enhance and restore the eye’s natural drainage system to provide sustained reduction of
intraocular pressure. Canaloplasty utilizes micro catheters in a simple and minimally invasive procedure. To perform a canaloplasty, a surgeon will create a tiny incision to gain access to Schlemm's canal. A microcatheter circumnavigates Schlemm's canal around the iris, enlarging the main drainage channel and its smaller collector channels through the injection of a sterile, gel-like material called viscoelastic. The catheter is then removed and a suture is placed within the canal and tightened. By opening Shlemm's canal, the pressure inside the eye is relieved. [https://mediamillinc.com/vjo.php?display=video&id=013] [http://www.jcrsjournal.org/article/S0886-3350(08)00004-7/abstract,] [http://www.jcrsjournal.org/article/S0886-3350(07)00697-9/abstract]
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