Niche cell

Niche cell

Niché cells are specific anatomic locations that regulate how stem-cell populations participate in tissue generation, maintenance and repair[1]. The niché performs several functions:

  • It may also induce pathologies by imposing aberrant function on stem cells or other targets[1].

The interplay between stem cells and their niché creates the dynamic system necessary for sustaining tissues, and for the ultimate design of stem-cell therapeutics[1].

References



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