Nodular fasciitis

Nodular fasciitis
Nodular fasciitis
Classification and external resources

Micrograph of nodular fasciitis showing the haphazard arrangement of cells (tissue culture-like pattern). H&E stain.
ICD-10 M72.4
ICD-9 728.79

Nodular fasciitis (also known as "Nodular pseudosarcomatous fasciits,"[1] "Pseudosarcomatous fasciitis,"[2], and "Subcutaneous pseudosarcomatous fibromatosis"[1]:992) is a benign[3] lesion most commonly found in the superficial fascia. It is most common in young persons on the upper extremities and trunk. Commonly mistaken for a sarcoma.

Contents

Etiology and clinical course

Similar to a dermatofibroma, it is believed to be a reparative process secondary to trauma, which is frequently not remembered. It evolves rapidly, but is usually less than 3 cm in diameter. There is an extremely low incidence of recurrence after resection.

Histology

  • Histologically vast array of patterns.
  • Short S-shaped fascicles, inflammation, accelerated mitotic index with normal mitoses.
  • Essentially spindle cell proliferation.
  • Stroma is rich in collagen and/or myxoid ground substance.

Additional images

  • Low mag.

  • Intermed. mag.

See also

References

  1. ^ a b Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0071380760.
  2. ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0. 
  3. ^ Sailon AM, Cappuccino G, Hameed M, Fleegler EJ (2008). "Nodular fasciitis of the hand over the metacarpophalangeal joint: a case report". Eplasty 8: e38. PMC 2491338. PMID 18725954. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2491338. 
v · d · eSoft tissue disorders / Rheumatism / Connective tissue arthropathy (M65–M79, 725–728)
Capsular joint
Bursopathy
Bursitis (Olecranon, Prepatellar, Trochanteric, Subacromial) · Synovial cyst (Baker's cyst) · Calcific bursitis
Noncapsular joint
Nonjoint

M: JNT

anat(h/c, u, t, l)/phys

noco(arth/defr/back/soft)/cong, sysi/epon, injr

proc, drug(M01C, M4)

M: MUS, DF+DRCT

anat (h/n, u, t/d, a/p, l)/phys/devp/hist

noco(m, s, c)/cong(d)/tumr, sysi/epon, injr

proc, drug (M1A/3)
v · d · eConnective/soft tissue tumors and sarcomas (ICD-O 8800–9059) (C45–C49/D17–D21, 171/214–215)
Not otherwise specified (8800–8809)
Connective tissue neoplasm
Fibromatous (8810–8839)
Fibroma/fibromatosis: Aggressive infantile fibromatosis · Aponeurotic fibroma · Collagenous fibroma · Diffuse infantile fibromatosis · Familial myxovascular fibromas · Fibroma of tendon sheath · Fibromatosis colli · Infantile digital fibromatosis · Juvenile hyaline fibromatosis · Plantar fibromatosis · Pleomorphic fibroma · Oral submucous fibrosis
Histiocytoma/histiocytic sarcoma: Benign fibrous histiocytoma · Malignant fibrous histiocytoma · Atypical fibroxanthoma
Solitary fibrous tumor
Myxomatous (8840–8849)
Fibroepithelial (9000–9039)
Synovial-like (9040–9049)
Lipomatous (8850–8889)
Chondroid lipoma · Intradermal spindle cell lipoma · Pleomorphic lipoma · Benign lipoblastomatosis · Spindle cell lipoma · Hibernoma
Myomatous (8890–8929)
general: Myoma/myosarcoma
skeletal muscle: Rhabdomyoma/rhabdomyosarcoma: Embryonal rhabdomyosarcoma (Sarcoma botryoides) · Alveolar rhabdomyosarcoma
Leiomyoma · Angioleiomyoma · Angiolipoleiomyoma · Genital leiomyoma · Leiomyosarcoma · Multiple cutaneous and uterine leiomyomatosis syndrome · Multiple cutaneous leiomyoma · Neural fibrolipoma · Solitary cutaneous leiomyoma
Complex mixed and stromal (8930–8999)
Mesothelial (9050–9059)

M: MUS, DF+DRCT

anat (h/n, u, t/d, a/p, l)/phys/devp/hist

noco(m, s, c)/cong(d)/tumr, sysi/epon, injr

proc, drug (M1A/3)

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