Cutaneous myxoma

Cutaneous Myxoma

A cutaneous myxoma, AKA superficial angiomyxoma, consists of a multilobulated myxoid mass containing stellate and/or spindled fibroblasts with pools of mucin forming cleft-like spaces. There is often a proliferation of blood vessels and an inflammatory infiltrate. Staining is positive for vimentin, negative for cytokeratin and desmin, and variable for CD34, Factor VIIIa, SMA^{[disambiguation needed ]}, MSA^{[disambiguation needed ]} and S-100.^[1]

Clinically, it may present as solitary or multiple flesh-colored nodules on the face, trunk, or extremities. It may occur as part of the Carney complex, and is sometimes the first sign. Local recurrence is common.^[2]

See also

• Skin lesion
• Myxoma

References

1. ^ Satter EK (October 2009). "Solitary superficial angiomyxoma: an infrequent but distinct soft tissue tumor". J. Cutan. Pathol. 36 (Suppl 1): 56–9. doi:10.1111/j.1600-0560.2008.01216.x. PMID 19187115. http://www3.interscience.wiley.com/cgi-bin/fulltext/121664953/HTMLSTART. 
2. ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology (10th ed.). Saunders. p. 614. ISBN 0-7216-2921-0. 

Lipomatous (8850–8889)

Lipoma/liposarcoma (Myelolipoma, Myxoid liposarcoma) · PEComa (Angiomyolipoma)

Chondroid lipoma · Intradermal spindle cell lipoma · Pleomorphic lipoma · Benign lipoblastomatosis · Spindle cell lipoma · Hibernoma

Myomatous (8890–8929)

general: Myoma/myosarcoma

smooth muscle: Leiomyoma/leiomyosarcoma

skeletal muscle: Rhabdomyoma/rhabdomyosarcoma: Embryonal rhabdomyosarcoma (Sarcoma botryoides) · Alveolar rhabdomyosarcoma

Leiomyoma · Angioleiomyoma · Angiolipoleiomyoma · Genital leiomyoma · Leiomyosarcoma · Multiple cutaneous and uterine leiomyomatosis syndrome · Multiple cutaneous leiomyoma · Neural fibrolipoma · Solitary cutaneous leiomyoma

Complex mixed and stromal (8930–8999)

Adenomyoma · Pleomorphic adenoma · Mixed Müllerian tumor · Mesoblastic nephroma · Wilms' tumor · Rhabdoid tumour · Clear-cell sarcoma of the kidney · Hepatoblastoma · Pancreatoblastoma · Carcinosarcoma

Mesothelial (9050–9059)

Mesothelioma · Adenomatoid tumor

see also Template:Connective tissue

M: MUS, DF+DRCT anat (h/n, u, t/d, a/p, l)/phys/devp/hist noco(m, s, c)/cong(d)/tumr, sysi/epon, injr proc, drug (M1A/3)