Mast cell sarcoma

Mast cell sarcoma
Mast cell sarcoma
Classification and external resources
ICD-10 C96.2
ICD-9 202.6
ICD-O: M9740/3
MeSH D012515

Mast cell sarcoma is an extremely aggressive[1] form of sarcoma made up of neoplastic mast cells. A sarcoma is a tumor made of cells from connective tissue. Mast cell sarcoma is an extremely rare tumor. Only 3 cases are reported so far. Prognosis is extremely poor. People with a mast cell sarcoma have no skin lesions, and pathology examination of the tumor shows it to be very malignant with an aggressive growth pattern.[2] Mast cell sarcoma should not be confused with extracutaneous mastocytoma, a rare benign mast cell tumor without destructive growth. In the cases observed, mast cell sarcoma terminated quickly as mast cell leukemia; one of the most aggressive human cancers. [3]

See also

References

  1. ^ Chott A, Guenther P, Huebner A, Selzer E, Parwaresch R, Horny H, Valent P (2003). "Morphologic and immunophenotypic properties of neoplastic cells in a case of mast cell sarcoma". Am J Surg Pathol 27 (7): 1013–9. doi:10.1097/00000478-200307000-00019. PMID 12826896. 
  2. ^ Nancy Gould, "Diagnosis and Classification of Mastocytosis", The Mastocytosis Society.
  3. ^ Ansell SM, ed (2008). Rare Hematological Malignancies. Cancer Treatment & Research. Springer. 
CFU-Baso
CFU-Eos
MEP CFU-Mast
Mastocytosis: Diffuse cutaneous mastocytosis · Erythrodermic mastocytosis · Generalized eruption of cutaneous mastocytosis (adult type) · Generalized eruption of cutaneous mastocytosis (childhood type) · Mast cell sarcoma · Solitary mastocytoma · Systemic mastocytosis · Xanthelasmoidal mastocytosis
Multiple/unknown

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