- Chronic eosinophilic leukemia
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Chronic eosinophilic leukemia Classification and external resources ICD-O: 9964/3 Chronic eosinophilic leukemia (CEL) is a disease in which too many eosinophils (a type of white blood cell) are found in the bone marrow, blood, and other tissues. CEL may stay the same for many years, or it may progress quickly to acute leukemia. It is generally caused by overactivation of the oncogene PDGFRA through a chromosome translocation event. Though a highly rare disease, CEL is extremely manageable with the use of Gleevec, which suppresses the oncogenic effects of PDGFRA.
External links
- Chronic eosinophilic leukemia entry in the public domain NCI Dictionary of Cancer Terms
This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".Myeloid hematological malignancy/leukemia histology (ICD-O 9590–9989, C81–C96, 200–208) CFU-GM/
and other granulocytesCFU-GMOtherCFU-BasoCFU-EosMP (Chronic eosinophilic leukemia/Hypereosinophilic syndrome)MEP CFU-MegCFU-EMD (Refractory anemia, Refractory anemia with excess of blasts, Chromosome 5q deletion syndrome, Sideroblastic anemia, Paroxysmal nocturnal hemoglobinuria, Refractory cytopenia with multilineage dysplasia)CFU-Mast Mastocytosis: Diffuse cutaneous mastocytosis · Erythrodermic mastocytosis · Generalized eruption of cutaneous mastocytosis (adult type) · Generalized eruption of cutaneous mastocytosis (childhood type) · Mast cell sarcoma · Solitary mastocytoma · Systemic mastocytosis · Xanthelasmoidal mastocytosisMultiple/unknown Categories:- Myeloid leukemia
- Rare diseases
- Medicine stubs
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