Sideroblastic anemia

Sideroblastic anemia

* With lead poisoning, see coarse basophilic stippling of red blood cells on peripheral blood smear
* Specific test: Prussian Blue stain of RBC in marrow. Shows ringed sideroblasts.


Occasionally, the anemia is so severe that support with transfusion is required. These patients usually do not respond to erythropoietin therapy. [cite book |author=Papadakis, Maxine A.; Tierney, Lawrence M.; McPhee, Stephen J. |title=Current Medical Diagnosis & Treatment, 2006 |publisher=McGraw-Hill Medical |location= |year=2005 |pages= |chapter=Sideroblastic Anemia |isbn=0-07-145410-1 |oclc= |doi= |accessdate=] Some cases have been reported that the anemia is reversed or heme level is improved through use of moderate to high doses of pyrodoxine (Vitamin B6.) In severe cases of SBA, bone marrow transplant is also an option with limited information about the success rate. Some cases are listed on MedLine and various other medical sites. In the case of isoniazid-induced sideroblastic anemia, the addition of B6 is sufficient to correct the anemia.

ee also

* Anemia
* Siderosis


External links

* [ Sideroblastic Anemias: Introduction - Information Center for Sickle Cell and Thalassemic Disorders ]
* [ A concise description of this group of diseases from the Iron Disorders Institute]
*RareDiseases|667|Anemia, Sideroblastic
*OMIM3|301310 RareDiseases|668|Anemia, sideroblastic spinocerebellar ataxia
*OMIM3|269950 RareDiseases|7644|Sideroblastic anemia, autosomal
*OMIM3|301300 RareDiseases|9456|X-linked sideroblastic anemia

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Look at other dictionaries:

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  • sideroblastic anaemia — noun refractory anemia characterized by sideroblasts in the bone marrow • Syn: ↑sideroblastic anemia, ↑siderochrestic anemia, ↑siderochrestic anaemia • Hypernyms: ↑refractory anemia, ↑refractory anaemia …   Useful english dictionary

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  • sideroachrestic anemia — sideroblastic anemia any of a heterogeneous group of acquired and hereditary anemias with diverse clinical manifestations; commonly characterized by large numbers of ringed sideroblasts in the bone marrow, ineffective erythropoiesis, variable… …   Medical dictionary

  • Anemia — The condition of having less than the normal number of red blood cells or less than the normal quantity of hemoglobin in the blood. The oxygen carrying capacity of the blood is, therefore, decreased. Persons with anemia may feel tired and fatigue …   Medical dictionary

  • anemia hypochromica sideroachrestica hereditaria — hereditary sideroblastic a …   Medical dictionary

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