- Megakaryocyte-erythroid progenitor cell
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Lineage. Captions in Polish, but "MEP" visible at bottom center.
The megakaryocyte-erythroid progenitor cell (or MEP, or hMEP to specify human[1]) is a cell that gives rise to megakaryocytes and erythrocytes.[2][3]
It is derived from the common myeloid progenitor.[4]
References
- ^ Mori Y, Iwasaki H, Kohno K, et al. (January 2009). "Identification of the human eosinophil lineage-committed progenitor: revision of phenotypic definition of the human common myeloid progenitor". J. Exp. Med. 206 (1): 183–93. doi:10.1084/jem.20081756. PMC 2626675. PMID 19114669. http://www.jem.org/cgi/pmidlookup?view=long&pmid=19114669.
- ^ MeSH Megakaryocyte-erythroid+progenitor+cells
- ^ "Blood -- On the origins of megakaryocytes". http://bloodjournal.hematologylibrary.org/cgi/content/full/109/4/1340. Retrieved 2009-03-04.
- ^ Edvardsson L, Dykes J, Olofsson T (May 2006). "Isolation and characterization of human myeloid progenitor populations--TpoR as discriminator between common myeloid and megakaryocyte/erythroid progenitors". Exp. Hematol. 34 (5): 599–609. doi:10.1016/j.exphem.2006.01.017. PMID 16647566. http://linkinghub.elsevier.com/retrieve/pii/S0301-472X(06)00068-3.
Myeloid physiology Hematopoiesis CFU-GMGranulopoiesis (Myeloblast, Promyelocyte, Myelocyte, Metamyelocyte, Band cell)
Monocytopoiesis (Monoblast, Promonocyte)MEPThrombopoiesis (Megakaryoblast, Promegakaryocyte)
Erythropoiesis (Proerythroblast, Normoblast, Reticulocyte)GeneralExtramedullary hematopoiesisHemostasis Other Erythrocyte aggregationMyeloid lineage - Blood (WBC and RBC) Cellular/
HSCsCFU-GMHistiocytes · Kupffer cells · Alveolar macrophage · Microglia · Osteoclasts · Epithelioid cells · giant cells (Langhans giant cells, Foreign-body giant cell, Touton giant cells)CFU-DLCommonCFU-BasoCFU-EosMEPCFU-MegCFU-ECFU-MastNoncellular Categories:- Microbiology
- Medicine stubs
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