Clot retraction

Clot retraction

Clot retraction is the "shrinking" of a blood clot over a number of days. In so doing, the edges of the blood vessel wall at the point of injury are slowly brought together again to repair the damage.

Clot retraction is dependent on release of multiple coagulation factors from platelets trapped in the fibrin mesh of the clot. Thus, failure to retract can be a sign of thrombocytopenia or a rare condition called Thrombasthenia.

Further reading

  • Arthur J. Vander, James H. Sherman, and Dorothy S. Luciano (1970). "Clot Retraction". Human Physiology: The Mechanisms of Body Function. McGraw-Hill. pp. 502. 
  • Nikolaos Skubas and George J. Despotis (1999). "Intraoperative Diagnosis and Therapy of Hemostatis Abnormalities with Cardiac Surgery". In Safuh Attar. Hemostasis in Cardiac. Blackwell Publishing. pp. 118–120. ISBN 0879934107. 

External links

General
Extramedullary hematopoiesis
Hemostasis
Coagulation (Fibrinolysis) · Clot retraction · Platelet adhesiveness
Other
Erythrocyte aggregation

M: MYL

cell/phys (coag, heme, immu, gran), csfs

rbmg/mogr/tumr/hist, sysi/epon, btst

drug (B1/2/3+5+6), btst, trns

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  • thrombasthenia — An abnormality of platelets characteristic of Glanzmann t.. SEE ALSO: Bernard Soulier syndrome. SYN: thromboasthenia. [thromb + G. astheneia, weakness] Glanzmann t. [MIM*273800] a hemorrhagic diathesis characterized by n …   Medical dictionary

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