Systematic (IUPAC) name
3-benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1,2,4- benzothiadiazine-7-sulfonamide
Clinical data
AHFS/ Consumer Drug Information
Pregnancy cat. Risk neonatal thrombocytopenia in 3rd trimester[1]
Legal status POM (UK)
Routes Oral
Pharmacokinetic data
Bioavailability 100%
Protein binding 96%
Metabolism extensive
Half-life 3-4 hours[2]
CAS number 73-48-3 YesY
ATC code C03AA01
PubChem CID 2315
DrugBank APRD00666
ChemSpider 2225 YesY
KEGG D00650 YesY
Chemical data
Formula C15H14F3N3O4S2 
Mol. mass 421.415 g/mol
SMILES eMolecules & PubChem
 N(what is this?)  (verify)

Bendroflumethiazide (INN), formerly bendrofluazide (BAN), is a thiazide diuretic used to treat hypertension.

It is also a fairly cheap drug, made cheap through mass production. Normal pharmaceutical trade prices vary from £0.10 - £0.20 for a 28 calendar pack of Bendroflumethiazide 2.5 tablets. Bendroflumethiazide (bendrofluazide) is a thiazide diuretic which works by inhibiting sodium absorption at the beginning of the distal convoluted tubule (DCT). Potassium is lost as a result of more sodium reaching the collecting ducts. Bendroflumethiazide has a role in the treatment of mild heart failure although loop diuretics are better for reducing overload. The main use of bendroflumethiazide currently is in hypertension (part of the effect is due to vasodilation).

Common adverse effects

Rare adverse effects


  1. ^ BNF 45 March 2003
  2. ^ Ed. Sean C. Sweetman, ed. Martindale: The complete drug reference (33 ed.). Pharmaceutical Press. 

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  • bendroflumethiazide — noun A thiazide diuretic used to treat hypertension Syn: bendrofluazide …   Wiktionary

  • bendroflumethiazide — A thiazide diuretic and antihypertensive agent. SYN: bendrofluazide. * * * (bendrofluazide) n. a potent thiazide diuretic used in the treatment of conditions involving retention of fluid, such as congestive heart failure, hypertension, and oedema …   Medical dictionary

  • bendroflumethiazide — bendrofluazide; n. a potent thiazide diuretic used in the treatment of conditions involving retention of fluid, such as congestive heart failure, hypertension, and oedema. Side effects include a fall in blood pressure on standing up, dizziness,… …   The new mediacal dictionary

  • bendrofluazide — bendroflumethiazide …   The new mediacal dictionary

  • ATC code C03 — A section of the Anatomical Therapeutic Chemical Classification System.C Cardiovascular systemC03A Low ceiling diuretics, thiazidesC03AA Thiazides, plain:C03AA01 Bendroflumethiazide:C03AA02 Hydroflumethiazide:C03AA03 Hydrochlorothiazide:C03AA04… …   Wikipedia

  • bendrofluazide — SYN: bendroflumethiazide. * * * see bendroflumethiazide * * * ben·dro·flu·a·zide (ben″dro flooґə zīd) bendroflumethiazide …   Medical dictionary

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