- Ductus arteriosus
Artery: Ductus arteriosus Plan of the fetal circulation. ("Ductus arteriosus" visible at upper right.) Heart cross-section with PDA Gray's subject #139 540 Source pulmonary artery Branches aortic arch Vein ductus venosus Precursor aortic arch 6 MeSH Ductus+Arteriosus
In the developing fetus, the ductus arteriosus (DA), also called the ductus Botalli, is a shunt connecting the pulmonary artery to the aortic arch. It allows most of the blood from the right ventricle to bypass the fetus's fluid-filled lungs. Upon closure at birth, it becomes the ligamentum arteriosum. There are two other fetal shunts, the ductus venosus and the foramen ovale.
Patent ductus arteriosus
Failure of a child's DA to close after birth results in a condition called patent ductus arteriosus and the generation of a left-to-right shunt. If left uncorrected, patency leads to pulmonary hypertension and possibly congestive heart failure and cardiac arrhythmias. Prostaglandins are responsible for maintaining the ductus arteriosus. Closure may be induced with NSAIDs because these drugs inhibit prostaglandin synthesis.
- ^ Pritchard & Korf. "Medical Genetics at a Glance". Blackwell Publishing. 2010. p63.
- Circulatory changes at birth at berkeley.edu
-  Ambient Air Pollution and Cardiovascular Malformations in Atlanta Georgia. This is a study showing a correlation between air pollution, particulate matter greater than 10 micrometers, that has statistical significance in increasing the risk of patent ductus arteriosus when inhaled by pregnant women at 3-7 weeks of pregnancy.
Prenatal development/Mammalian development of circulatory system (GA 5, TE E5.11) Heart developmentTubular heartSepta/ostiaOtherAtrioventricular canal · Primary interventricular foramen Vasculogenesis,
Blood island of umbilical vesicleDevelopment of arteriesDevelopment of veinsAnterior cardinal vein · Posterior cardinal vein · Common cardinal veinsDevelopment of lymph vesselsLymph sacsDevelopment of circulatory system about teeth near childrenanuli: Anulus sanguineus perienameleus · lacunae: Lacuna sanguinea supraenamelea (Ductus sanguineus mesialis · Ductus sanguineus distalis · Ductus sanguineus lingualis · Ductus sanguineus palatinus · Ductus sanguineus buccalis · Ductus sanguineus labialis), Lacuna sanguinea apicalis, Lacuna sanguinea periodontalis, Lacuna sanguinea parodontalis, Lacuna sanguinea gingivalis
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